推荐产品
等級
analytical standard
品質等級
化驗
≥95%
技術
HPLC: suitable
gas chromatography (GC): suitable
mp
122-123 °C
應用
forensics and toxicology
pharmaceutical (small molecule)
格式
neat
儲存溫度
−20°C
SMILES 字串
Cl.CCCC(C(=O)OCCN(CC)CC)(c1ccccc1)c2ccccc2
InChI
1S/C23H31NO2.ClH/c1-4-17-23(20-13-9-7-10-14-20,21-15-11-8-12-16-21)22(25)26-19-18-24(5-2)6-3;/h7-16H,4-6,17-19H2,1-3H3;1H
InChI 密鑰
FHIKZROVIDCMJA-UHFFFAOYSA-N
基因資訊
human ... NOS1(4842) , NOS2(4843) , NOS2B(201288) , NOS2C(645740) , NOS3(4846)
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應用
有关合适的仪器技术的更多信息，请参阅产品的分析证书。如需进一步支持，请联系技术服务。
盐酸普瑞迪芬可用作内标，用气相色谱-质谱联用（GC-MS）测定人尿样中的 O-去甲基曲马多、曲马多和 N-去甲基曲马多镇痛剂。
生化／生理作用
阻断格列本脲敏感 K+ 通道。抑制神经元性一氧化氮合成酶和细胞色素 P450
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
Simultaneous determination of tramadol, O-desmethyltramadol and N-desmethyltramadol in human urine by gas chromatography?mass spectrometry
El-Sayed Y A-A, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 926, 9-15 (2013)
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Drug metabolism and disposition: the biological fate of chemicals, 36(12), 2539-2546 (2008-09-19)
When incubated with human liver microsomes, 2-diethylaminoethyl-2,2-diphenylvalerate-HCl (SKF525A) undergoes cytochrome P450 (P450)-dependent oxidative N-deethylation to the secondary amine metabolite 2-ethylaminoethyl-2,2-diphenylvalerate (SKF8742). P450-selective inhibitors indicated CYP3As catalyzed this reaction, and the deethylation rate correlated best with the CYP3A activity across a
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Adverse reactions of acetaminophen have been associated to oxidative stress, which may be elicited by reactive oxygen species (ROS) and/or production of the metabolite NAPQI. Both phenomena would arise through the activity of liver cytochrome P450 (CYP450) system, but their
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