推荐产品
product name
(±)-氯胺酮 盐酸盐, solid
形狀
solid
品質等級
藥物控制
USDEA Schedule III; stupéfiant (France); regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain)
儲存溫度
2-8°C
SMILES 字串
Cl.CNC1(CCCCC1=O)c2ccccc2Cl
InChI
1S/C13H16ClNO.ClH/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14;/h2-3,6-7,15H,4-5,8-9H2,1H3;1H
InChI 密鑰
VCMGMSHEPQENPE-UHFFFAOYSA-N
基因資訊
human ... GRIN1(2902) , GRIN2A(2903) , GRIN2B(2904) , GRIN2C(2905) , GRIN2D(2906) , GRIN3A(116443) , GRIN3B(116444)
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生化／生理作用
Selective NMDA glutamate receptor antagonist; veterinary anesthetic.
特點和優勢
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral - STOT SE 3
標靶器官
Central nervous system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
其他客户在看
R V Pustovit et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 27(5), 610-617 (2015-01-24)
Despite constipation being a common problem, the treatments that are available have side effects and are only partly effective. Recent studies show that centrally penetrant ghrelin receptor agonists cause defecation in humans and other species. Here, we describe some features
Ege T Kavalali et al.
The American journal of psychiatry, 169(11), 1150-1156 (2013-03-28)
Recent clinical studies have demonstrated that a single subpsychotomimetic dose of ketamine, an ionotropic glutamatergic N-methyl-D-aspartate (NMDA) receptor antagonist, produces a rapid antidepressant response in patients with major depressive disorder, with effects lasting up to 2 weeks. Despite enthusiasm about
Scott A Schobel et al.
Neuron, 78(1), 81-93 (2013-04-16)
The hippocampus in schizophrenia is characterized by both hypermetabolism and reduced size. It remains unknown whether these abnormalities are mechanistically linked. Here we addressed this question by using MRI tools that can map hippocampal metabolism and structure in patients and
James W Murrough et al.
The American journal of psychiatry, 170(10), 1134-1142 (2013-08-29)
Ketamine, a glutamate N-methyl-d-aspartate (NMDA) receptor antagonist, has shown rapid antidepressant effects, but small study groups and inadequate control conditions in prior studies have precluded a definitive conclusion. The authors evaluated the rapid antidepressant efficacy of ketamine in a large
Songen Zhang et al.
Journal of leukocyte biology, 97(6), 1003-1010 (2015-01-15)
Streptococcus pyogenes of the M1 serotype can cause STSS, which is associated with significant morbidity and mortality. The purpose of the present study was to examine the role of NFAT signaling in M1 protein-induced lung injury. NFAT-luc mice were treated
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