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About This Item
经验公式（希尔记法）:
C13H8F2O3
CAS号:
分子量:
250.20
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24
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等級
analytical standard
品質等級
技術
HPLC: suitable
gas chromatography (GC): suitable
應用
forensics and toxicology
pharmaceutical (small molecule)
格式
neat
SMILES 字串
FC1=CC(F)=CC=C1C2=CC(C(O)=O)=C(O)C=C2
InChI
1S/C13H8F2O3/c14-8-2-3-9(11(15)6-8)7-1-4-12(16)10(5-7)13(17)18/h1-6,16H,(H,17,18)
InChI 密鑰
HUPFGZXOMWLGNK-UHFFFAOYSA-N
基因資訊
human ... ALB(213) , PTGS1(5742) , PTGS2(5743)
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應用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
訊號詞
Warning
危險分類
Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
其他客户在看
Ellen Y Cotrina et al.
Journal of medicinal chemistry, 56(22), 9110-9121 (2013-10-24)
The amyloidogenic protein transthyretin (TTR) is thought to aggregate into amyloid fibrils by tetramer dissociation which can be inhibited by a number of small molecule compounds. Our analysis of a series of crystallographic protein-inhibitor complexes has shown no clear correlation
Teresa Mairal et al.
PloS one, 4(1), e4124-e4124 (2009-01-07)
The thyroid hormone and retinol transporter protein known as transthyretin (TTR) is in the origin of one of the 20 or so known amyloid diseases. TTR self assembles as a homotetramer leaving a central hydrophobic channel with two symmetrical binding
John L Berk et al.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 19 Suppl 1, 37-38 (2012-05-04)
Familial amyloidotic polyneuropathy (FAP) is a protein folding disorder that induces neuropathy and cardiomyopathy, leading to death within 7-15 years after onset of clinical disease. In vitro, small ligands binding the thyroid hormone docking site stabilize tetrameric transthyretin, inhibiting amyloid
Maria Esther Zugasti et al.
Drug development and industrial pharmacy, 35(10), 1264-1270 (2009-06-27)
The influence of beta-cyclodextrin (beta-CD) polymers on drug release from hydroxypropyl methylcellulose (HPMC) matrices has not been reported in the literature. The influence of monomeric beta-CD and both soluble and insoluble beta-CD polymers on drug release from tablets containing either
J A Murillo Pulgarín et al.
Analytica chimica acta, 625(1), 47-54 (2008-08-30)
The simultaneous determination of 6-methoxy-2-naphthylacetic acid (6MNA) and diflunisal in serum samples using the combination of matrix isopotential synchronous fluorescence (MISF) and first derivative technique is proposed. 6MNA and diflunisal exhibit overlapped spectra and serum produces background fluorescence that precludes
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