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Merck

B4380

Sigma-Aldrich

溴乙烷

≥97% purity, powder

别名:

单溴代二苯甲烷

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About This Item

经验公式(希尔记法):
C10H11BrN2O2
CAS号:
分子量:
271.11
Beilstein:
4430959
MDL號碼:
分類程式碼代碼:
12171500
PubChem物質ID:
NACRES:
NA.47

product name

溴乙烷, ≥97% (HPLC)

品質等級

化驗

≥97% (HPLC)

形狀

powder

顏色

yellow

mp

161 °C

溶解度

acetonitrile: 20 mg/mL

&epsilon ;(消光係數)

4.6-5.1 at 396-398 nm in H2O

應用

diagnostic assay manufacturing
hematology
histology

儲存溫度

−20°C

SMILES 字串

CC1=C(C)C(=O)N2N1C(CBr)=C(C)C2=O

InChI

1S/C10H11BrN2O2/c1-5-7(3)12-8(4-11)6(2)10(15)13(12)9(5)14/h4H2,1-3H3

InChI 密鑰

AHEWZZJEDQVLOP-UHFFFAOYSA-N

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一般說明

溴代双满又称单溴联苯胺。它还是一种已知的硫醇探针,是一种在光解反应后活化的荧光试剂。

應用

溴代双满用于高效液相色谱法硫醇测定,适于荧光测定2,3-二巯基丙烷-1-磺酸和其他二硫醇。溴代双满已用作研究牛心线粒体寡霉素敏感性 ATP 酶的荧光标记。
此物质可用于体外游离硫化氢的定量测定。它已用于标记含有硫醇基的蛋白质。

生化/生理作用

溶液形式的溴代双满可与小分子硫醇基(如 GSH)和反应性蛋白硫醇基(如血红蛋白)反应。溴代双满与硫醇的反应为二级pH依赖性反应,且在与硫醇盐反应后,可活化水溶性荧光产物以便检测。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Bromobimane probes for thiols.
E M Kosower et al.
Methods in enzymology, 251, 133-148 (1995-01-01)
N S Kosower et al.
Proceedings of the National Academy of Sciences of the United States of America, 76(7), 3382-3386 (1979-07-01)
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Differing effects of mechanical dough development and sheeting development methods on aggregated glutenin proteins.
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Cereal Chem., 80.6, 707-711 (2003)
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G protein-coupled receptors (GPCRs) mediate the majority of physiologic responses to hormones and neurotransmitters. However, many GPCRs exhibit varying degrees of agonist-independent G protein activation. This phenomenon is referred to as basal or constitutive activity. For many of these GPCRs
Edward A Wintner et al.
British journal of pharmacology, 160(4), 941-957 (2010-07-02)
Hydrogen sulphide (H(2)S) is a labile, endogenous metabolite of cysteine, with multiple biological roles. The development of sulphide-based therapies for human diseases will benefit from a reliable method of quantifying H(2)S in blood and tissues. Concentrations of reactive sulphide in

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