推荐产品
品質等級
產品線
TraceCERT®
等級
TraceCERT®
形狀
solid
儲存期限
limited shelf life, expiry date on the label
製造商／商標名
Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
技術
qNMR: suitable
mp
143-146 °C (lit.)
應用
cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical
SMILES 字串
OC(=O)CP(O)(O)=O
InChI
1S/C2H5O5P/c3-2(4)1-8(5,6)7/h1H2,(H,3,4)(H2,5,6,7)
InChI 密鑰
XUYJLQHKOGNDPB-UHFFFAOYSA-N
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一般說明
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.
Check out our entire range of quantitative NMR standards (qNMR standards)
應用
- Enhancing Guide RNA Stability and Editing Yields: Phosphonoacetate modifications have been shown to significantly enhance the stability and editing efficiency of guide RNAs for Cas9-based genome editors. This development has profound implications in genetic engineering and therapeutic applications, where precision and stability are crucial (Ryan et al., 2023).
- Glomerular and Tubulointerstitial Nephropathy Study: Phosphonoacetic acid has been indirectly related to studies on kidney diseases such as glomerular and tubulointerstitial nephropathy, showcasing its potential relevance in medical research to understand and treat complex renal conditions (Pleško et al., 2021).
- Environmental Impact of Phosphonoacetate: Research on PMIDA-modified magnetic nanoparticles, including those related to phosphonoacetate, explores their application in liver MRI, indicating its utility in enhancing diagnostic imaging techniques and its potential environmental implications (Demin et al., 2018).
- CRISPR-Cas Specificity Improvement: Modifications including phosphonoacetate derivatives have been employed to improve the specificity and efficiency of CRISPR-Cas systems in gene editing, underscoring the chemical′s role in cutting-edge biotechnological research (Ryan et al., 2018).
- Cardiovascular Pharmacology: Studies involving phosphonoacetic acid have been connected to cardiovascular pharmacology, particularly in exploring the mechanisms that inhibit calcification in vascular tissues, which is vital for developing treatments for vascular calcification diseases (Duan et al., 2017).
推薦產品
法律資訊
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
商品
The use of CRMs for the NMR quantification of phosphorylated organic compounds and metabolites offers several advantages as it is based on a signal comparison of the analyte with an internal or external reference standard.
The use of CRMs for the NMR quantification of phosphorylated organic compounds and metabolites offers several advantages as it is based on a signal comparison of the analyte with an internal or external reference standard.
In certain cases, 1H qNMR reaches its limits, especially regarding the certification of complex and larger molecules. However, new fields of application often also bring along the presence of heteroatoms, namely 31P and 19F. We therefore introduced 3 CRMs for 19F qNMR with traceability to the SI.
In certain cases, 1H qNMR reaches its limits, especially regarding the certification of complex and larger molecules. However, new fields of application often also bring along the presence of heteroatoms, namely 31P and 19F. We therefore introduced 3 CRMs for 19F qNMR with traceability to the SI.
相关内容
ChemisTwin is your new online digital assistant for NMR result interpretation. It will save you time by automating the interpretation of routine NMR analysis for structure confirmation as well as quantitative NMR (qNMR) measurements using qNMR eRMs from our verified electronic Reference Materials database.
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