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Supelco

双氯芬酸 钠盐

analytical standard

别名:

2-[（2,6-二氯苯基）氨基]苯乙酸 钠盐

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About This Item

经验公式（希尔记法）:
C14H10Cl2NNaO2
CAS号:
15307-79-6
分子量:
318.13
EC號碼:
239-346-4
MDL號碼:
MFCD00082251
分類程式碼代碼:
41116107
PubChem物質ID:
329770242
NACRES:
NA.24

等級

analytical standard

品質等級

100

化驗

≥98.5% (HPLC)

儲存期限

limited shelf life, expiry date on the label

技術

HPLC: suitable
gas chromatography (GC): suitable

雜質

≤2.0% water

應用

forensics and toxicology
pharmaceutical (small molecule)

格式

neat

SMILES 字串

[Na+].[O-]C(=O)Cc1ccccc1Nc2c(Cl)cccc2Cl

InChI

1S/C14H11Cl2NO2.Na/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19;/h1-7,17H,8H2,(H,18,19);/q;+1/p-1

InChI 密鑰

KPHWPUGNDIVLNH-UHFFFAOYSA-M

基因資訊

human ... PTGS1(5742) , PTGS2(5743)

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應用

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生化／生理作用

标准NSAID和环加氧酶（COX）抑制剂。主要代谢物是4′-羟基二苯甲酸和5′-羟基二氯芬酸。已被用作CYP2C9的选择性底物。

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訊號詞

Danger

危險分類

Acute Tox. 3 Oral - Aquatic Chronic 2 - Repr. 2 - STOT RE 1

儲存類別代碼

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

从最新的版本中选择一种：

分析证书(COA)

Lot/Batch Number
BCCG2967
BCCC9868
BCBV8839
BCBZ8907
BCBX0728

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Scientific reports, 9(1), 3153-3153 (2019-03-01)
In the recent years, cancer research succeeded with sensitive detection methods, targeted drug delivery systems, and the identification of a large set of genes differently expressed. However, although most therapies are still based on antimitotic agents, which are causing wide
R N Brogden et al.
Drugs, 20(1), 24-48 (1980-07-01)
Diclofenac sodium, a phenylacetic acid derivative, is a non-steroidal, anti-inflammatory, analgesic agent advocated for use in rheumatoid arthritis, degenerative joint disease, ankylosing spondylitis and allied conditions, and in the treatment of pain resulting from minor surgery, trauma and dysmenorrhoea. Published
D Aygün et al.
Histology and histopathology, 27(4), 417-436 (2012-03-01)
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for the purpose of anti-inflammation, antipyretic, and analgesia. For this aim, they are used for the alleviation of pain, fever, and inflammation associated with rheumatoid arthritis, sports injuries, and temporary pain. However, treatment
Paul L McCormack et al.
Drugs, 68(1), 123-130 (2007-12-18)
*A new formulation of the nonselective NSAID diclofenac sodium suitable for intravenous bolus injection has been developed using hydroxypropyl beta-cyclodextrin as a solubility enhancer (HPbetaCD diclofenac). * HPbetaCD diclofenac intravenous bolus injection was shown to be bioequivalent to the existing
R E Small
Clinical pharmacy, 8(8), 545-558 (1989-08-01)
The pharmacology, pharmacokinetics, clinical efficacy, adverse effects, and dosage of diclofenac sodium are reviewed. Diclofenac, the first nonsteroidal anti-inflammatory agent (NSAID) to be approved that is a phenylacetic acid derivative, competes with arachidonic acid for binding to cyclo-oxygenase, resulting in
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