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About This Item
经验公式（希尔记法）:
C24H9Br4NO7
CAS号:
分子量:
742.95
MDL號碼:
分類程式碼代碼:
12352207
PubChem物質ID:
NACRES:
NA.32
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等級
for fluorescence
品質等級
化驗
≥93% (HPLC)
螢光
λex 524 nm; λem 545 nm (after derivatization with 2-mercaptoethanol)
儲存溫度
2-8°C
SMILES 字串
Oc1c(Br)cc2c(Oc3c(Br)c(O)c(Br)cc3C24OC(=O)c5cc(ccc45)N6C(=O)C=CC6=O)c1Br
InChI
1S/C24H9Br4NO7/c25-13-6-11-21(17(27)19(13)32)35-22-12(7-14(26)20(33)18(22)28)24(11)10-2-1-8(5-9(10)23(34)36-24)29-15(30)3-4-16(29)31/h1-7,32-33H
InChI 密鑰
YRCLWXRIEYQTAV-UHFFFAOYSA-N
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相关类别
一般說明
5-马来酰亚胺-伊红，也称为 EMA 或伊红-5-马来酰亚胺，是一种荧光结合剂。5-马来酰亚胺-伊红结合试验可测量 EMA 标记细胞减少的平均通道荧光（MCF）读数。
應用
伊红-5-马来酰亚胺已被用作人红细胞带 3 蛋白的荧光探针。 它被广泛用作实验室诊断探针，以通过流式细胞术检测遗传性球形红细胞增多症（HS）。 伊红-5-马来酰亚胺结合试验已用于分析阿勒替尼（一线治疗）对于变性淋巴瘤激酶（ALK）的效果。
其他說明
三重探针。测量蛋白质在溶液和膜中的旋转扩散，包括肌球蛋白和丙酮酸脱氢酶
相關產品
产品编号
说明
价格
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
S Ishiwata et al.
The Journal of biological chemistry, 262(17), 8314-8317 (1987-06-15)
We studied the rotational Brownian motions of myosin heads, of which the sulfhydryl group was selectively labeled with the triplet probe 5-eosinylmaleimide, in myofibril by using flash-induced phosphorescence anisotropy decay measurements. The anisotropy decay curve under relaxing conditions consisted of
Renée L Crisp et al.
Pediatric blood & cancer, 59(7), 1299-1301 (2012-04-11)
We studied 31 children with hemolytic anemia, or with positive family history for hereditary spherocytosis (HS), to assess the reliability of capillary blood samples for the diagnosis. HS was diagnosed in 20 patients. Cryohemolysis (CH) was positive in 94% and
Delay in the measurement of eosin-5'-maleimide (EMA) binding does not affect the test result for the diagnosis of hereditary spherocytosis.
Ciepiela O, Kotula I, Gorska E, et al.
Clinical Chemistry and Laboratory Medicine, 0, 1-7 (2012)
Paola Bianchi et al.
Haematologica, 97(4), 516-523 (2011-11-08)
The laboratory diagnosis of hereditary spherocytosis commonly relies on NaCl-based or glycerol-based red cell osmotic fragility tests; more recently, an assay directly targeting the hereditary spherocytosis molecular defect (eosin-5'-maleimide-binding test) has been proposed. None of the available tests identifies all
A J Visser et al.
European journal of biochemistry, 121(1), 233-235 (1981-12-01)
The enzymatically reduced lipoyl residues of the transacetylase component of the pyruvate dehydrogenase complex from Escherichia coli were labeled with eosin maleimide. Using eosin as triplet probe, triplet-triplet absorption dichroism measurements were performed to obtain rotational correlation times of the
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