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Merck

52517

Supelco

1,1,1,3,3,3-六氟-2-丙醇

for GC derivatization, LiChropur, ≥99.8%

别名:

HFP, 六氟异丙醇

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About This Item

线性分子式:
(CF3)2CHOH
CAS号:
分子量:
168.04
Beilstein:
1841007
EC號碼:
MDL號碼:
分類程式碼代碼:
12352104
PubChem物質ID:
NACRES:
NA.05

等級

for GC derivatization

品質等級

化驗

≥99.8% (GC)
≥99.8%

品質

LiChropur

反應適用性

reagent type: derivatization reagent
reaction type: Acylations

reagent type: derivatization reagent
reaction type: Esterifications

技術

gas chromatography (GC): suitable

折射率

n20/D 1.275 (lit.)

bp

59 °C (lit.)

mp

−4 °C (lit.)

密度

1.596 g/mL at 25 °C (lit.)

SMILES 字串

OC(C(F)(F)F)C(F)(F)F

InChI

1S/C3H2F6O/c4-2(5,6)1(10)3(7,8)9/h1,10H

InChI 密鑰

BYEAHWXPCBROCE-UHFFFAOYSA-N

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一般說明

六氟异丙醇(HFP)通常用于天然状态蛋白质变性,还能稳定未折叠多肽和蛋白质,如ß-乳球蛋白和蜂毒素的a-螺旋构型。

應用

适于衍生化谷氨酸、高香草酸、异香草醛和二羟基苯乙酸和Υ-氨基丁酸。

其他說明

1,1,1,3,3,3-六氟-2-丙醇中的尺寸排阻色谱
六氟异丙基酯、N-五氟丙基和三氟乙酰基的衍生化试剂。

法律資訊

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

象形圖

Health hazardCorrosion

訊號詞

Danger

危險聲明

危險分類

Eye Dam. 1 - Repr. 2 - Skin Corr. 1A - STOT RE 2

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類(WGK)

WGK 2

閃點(°F)

No data available

閃點(°C)

No data available

個人防護裝備

Faceshields, Gloves, Goggles


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Thomas H Mourey et al.
Journal of chromatography. A, 964(1-2), 169-178 (2002-08-30)
1,1,1,3,3,3-Hexafluoroisopropanol is re-examined as an eluent for size-exclusion chromatography (SEC) of polyesters, nylons, and other polar polymers. It is shown that anomalous SEC behavior reported in previous literature can be eliminated by adding 0.01 M tetraethylammonium nitrate to the eluent.
Cooperative a-helix formation of ?-lactoglobulin and melittin induced by hexafluoroisopropanol
Hirota, Nami, Yuji Goto, and Kazuko Mizuno.
Protein Science, 6 (2), 416-421 (1997)
Sriya Das et al.
ACS applied materials & interfaces, 3(6), 1844-1851 (2011-05-05)
We demonstrate a novel in situ polymerization technique to develop localized polymer coatings on the surface of dispersed pristine graphene sheets. Graphene sheets show great promise as strong, conductive fillers in polymer nanocomposites; however, difficulties in dispersion quality and interfacial
Dave W Chen et al.
International journal of pharmaceutics, 430(1-2), 335-341 (2012-04-24)
This study investigated the in vitro release of vancomycin, gentamicin, and lidocaine from novel electrospun sandwich-structured polylactide-polyglycolide (PLGA)/collagen nanofibrous membranes. For the electrospinning of biodegradable membranes, PLGA/collagen and PLGA/vancomycin/gentamicin/lidocaine were separately dissolved in 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP). They were then electrospun into
Benjamin H Rotstein et al.
Chemical communications (Cambridge, England), 48(31), 3775-3777 (2012-03-21)
A novel class of reagents, thioester isocyanides, have been prepared and applied in the synthesis of peptide macrocycles. The isocyanide part of the molecule is deployed in a multicomponent macrocyclization step. This step is followed by chemoselective peptide ligation at

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