46256

红霉素 A 二水合物

VETRANAL^®, analytical standard

• 经验公式（希尔记法）: C₃₇H₆₇NO₁₃ · xH₂O
• CAS号: 207291-29-0
• 分子量: 733.93 (anhydrous basis)
• EC號碼: 204-040-1
• MDL號碼: MFCD16661001
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329757110
• NACRES: NA.24

属性

• 等級: analytical standard
• 品質等級: 200
• 產品線: VETRANAL^®
• 儲存期限: limited shelf life, expiry date on the label
• 技術: HPLC: suitable; gas chromatography (GC): suitable
• 應用: clinical testing
• 形式: neat
• SMILES 字串: N([C@@H]1[C@H]([C@@H](O[C@@H](C1)C)O[C@@H]2[C@H]([C@@H]([C@H](C(=O)O[C@@H]([C@]([C@@H]([C@H](C(=O)C(C[C@]2(O)C)C)C)O)(O)C)CC)C)O[C@@H]3O[C@H]([C@@H]([C@@](C3)(OC)C)O)C)C)O)(C)C.O.O
• InChI: 1S/C37H67NO13.2H2O/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26;;/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3;2*1H2/t18?,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-;;/m1../s1
• InChI 密鑰: IWGQNYZQLVGGCS-ZKSNWDMWSA-N

说明

應用

Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

生化／生理作用

Mode of Action: Erythromycin acts by inhibiting elongation at the transpeptidation step, specifically aminoacyl translocation from the A-site to P-site.

Antimicrobial Spectrum: This product acts against both gram-negative and gram-positive bacteria.

注意

This product is stable in solution at 37°C for 3 days. Stock solutions should be stored at 2-8°C.

準備報告

This product is soluble in water at 2 mg/mL, with a 0.067% solution in water yielding a pH of 8.0-10.5. It is also soluble in ethanol at 50 mg/mL, yielding a clear, colorless to faint yellow solution. It is freely soluble in alcohol, acetone, chloroform, acetonitrile and ethyl acetate but forms salts with acids. All solutions should be protected from light.

法律資訊

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)