43999
5-Hydroxyomeprazole
analytical standard
别名:
4-Methoxy-6-{[(5-methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl}-5-methyl-3-pyridinemethanol, 5-Methoxy-2-{[(5-hydroxymethyl-4-methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole
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所有图片(2)
About This Item
经验公式（希尔记法）:
C17H19N3O4S
CAS号:
分子量:
361.42
Beilstein:
8439890
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24
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等級
analytical standard
品質等級
化驗
≥95.0% (HPLC)
儲存期限
limited shelf life, expiry date on the label
技術
HPLC: suitable
gas chromatography (GC): suitable
應用
forensics and toxicology
pharmaceutical (small molecule)
格式
neat
儲存溫度
2-8°C
SMILES 字串
O=S(CC1=NC=C(CO)C(OC)=C1C)C2=NC3=CC(OC)=CC=C3N2
InChI
1S/C17H19N3O4S/c1-10-15(18-7-11(8-21)16(10)24-3)9-25(22)17-19-13-5-4-12(23-2)6-14(13)20-17/h4-7,21H,8-9H2,1-3H3,(H,19,20)
InChI 密鑰
CMZHQFXXAAIBKE-UHFFFAOYSA-N
相关类别
應用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
訊號詞
Warning
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Ersin Gumus et al.
European journal of clinical pharmacology, 68(5), 629-636 (2011-11-15)
Lansoprazole, a cytochrome P450 2C19 (CYP2C19) substrate, has been widely used in children to manage acid-related diseases. CYP2C19 exhibits marked genetic polymorphisms, and distribution of these polymorphisms varies among different ethnic groups. There is limited data regarding the use of
Jeanette Olsson et al.
Journal of chromatography. A, 1129(2), 291-295 (2006-07-21)
This study demonstrates the development and validation of a non-aqueous capillary electrophoresis (NACE) method for enantiomeric determination of omeprazole and its metabolite 5-hydroxyomeprazole. Heptakis-(2,3-di-O-methyl-6-O-sulfo)-beta-cyclodextrin (HDMS-beta-CD) was chosen as the chiral selector in an ammonium acetate buffer acidified with formic acid
Joanne Roberts et al.
Rapid communications in mass spectrometry : RCM, 32(12), 929-941 (2018-03-24)
Omeprazole is used to treat gastric disorders and is one of the most commonly consumed drugs in the western world. It forms several metabolites but is mostly excreted unchanged and as 5-hydroxyomeprazole. Since omeprazole is widely prescribed, its excretion from
Valerie A Frerichs et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 824(1-2), 71-80 (2005-07-20)
A method has been developed and validated for the quantitation of midazolam, alphahydroxy-midazolam, omeprazole, and hydroxyomeprazole from one 250 microL sample of human plasma using high performance liquid chromatography coupled to tandem mass spectrometry. The method was validated for a
J Olsson et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 875(1), 329-332 (2008-06-25)
The present paper demonstrates the enantiomeric separation of omeprazole and its metabolite 5-hydroxyomeprazole performed with open tubular capillary electrochromatography (OT-CEC). The protein avidin was used as the chiral selector. Avidin was immobilized by a Schiffs base type of reaction where
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