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34029

Supelco

黄曲霉素 B1 溶液

2 μg/mL in acetonitrile, analytical standard

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About This Item

经验公式（希尔记法）:
C17H12O6
CAS号:
1162-65-8
分子量:
312.27
Beilstein:
1269174
EC號碼:
200-835-2
MDL號碼:
MFCD00869647
分類程式碼代碼:
85151701
PubChem物質ID:
329754767
NACRES:
NA.24

等級

analytical standard

品質等級

100

儲存期限

limited shelf life, expiry date on the label

濃度

2 μg/mL in acetonitrile

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

cleaning products
cosmetics
food and beverages
personal care

格式

single component solution

儲存溫度

−20°C

SMILES 字串

[H][C@]12OC=C[C@@]1([H])c3c(O2)cc(OC)c4C5=C(C(=O)CC5)C(=O)Oc34

InChI

1S/C17H12O6/c1-20-10-6-11-14(8-4-5-21-17(8)22-11)15-13(10)7-2-3-9(18)12(7)16(19)23-15/h4-6,8,17H,2-3H2,1H3/t8-,17+/m0/s1

InChI 密鑰

OQIQSTLJSLGHID-WNWIJWBNSA-N

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相关类别

一般說明

Aflatoxin B1 is a mycotoxin found to be hepatocarcinogenic in nature. It has a strong affinity for the deoxyribonucleic acid (DNA) and binds to both native and denatured deoxyribonucleic acid (DNA) as indicated by spectroscopy and equilibrium dialysis results. This fungal metabolic product is commonly found in food and feed, contaminated by Aspergillus species.

The product is supplied in CERTAN® vial.

應用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Aflatoxin B1 solution may be used as an analytical reference standard for the determination of the analyte in meat, meat products, eggs and milk using high-performance liquid chromatography (HPLC) with fluorescence and ultraviolet detection.

法律資訊

CERTAN is a registered trademark of LGC Group

相關產品

产品编号
说明
价格

象形圖

FlameExclamation mark
GHS02,GHS07

訊號詞

Danger

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

儲存類別代碼

3 - Flammable liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

35.6 °F - closed cup

閃點（°C）

2 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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分析证书(COA)

Lot/Batch Number
BCCK3016
BCCH9875
BCCH4024
BCCH1789
BCCG5931

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Aflatoxin B1 induces the transversion of G-> T in codon 249 of the p53 tumor suppressor gene in human hepatocytes.
Aguilar F, et al.
Proceedings of the National Academy of Sciences of the USA, 90(18), 8586-8590 (1993)
Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1.
McGlynn AK, et al.
Proceedings of the National Academy of Sciences of the USA, 92(6), 2384-2387 (1995)
M B Sporn et al.
Science (New York, N.Y.), 151(3717), 1539-1541 (1966-03-25)
Aflatoxin B(1) binds to both native and denatured DNA, as shown by spectroscopy and equilibrium dialysis. It also strongly inhibits incorporation of cytidine into rat liver nuclear RNA and lowers the RNA content of the nucleus. The extremle toxicity and
Anna Z Wec et al.
Cell host & microbe, 25(1), 39-48 (2019-01-11)
Passive administration of monoclonal antibodies (mAbs) is a promising therapeutic approach for Ebola virus disease (EVD). However, all mAbs and mAb cocktails that have entered clinical development are specific for a single member of the Ebolavirus genus, Ebola virus (EBOV)
Determination of aflatoxins in eggs, milk, meat and meat products using HPLC fluorescent and UV detectors.
Herzallah MS.
Food Chemistry, 114(3), 1141-1146 (2009)
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