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Merck
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文件

16682

Sigma-Aldrich

(R)-泛酸 钠盐

≥95% (GC)

别名:

(2R)-2,4-二羟基-3,3-二甲基丁酸 单钠盐, (R)-2,4-二羟基-3,3-二甲基丁酸 钠盐, 钠 (R)-泛酸, 钠D-泛酸

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About This Item

经验公式（希尔记法）:
C6H11NaO4
CAS号:
60979-68-2
分子量:
170.14
Beilstein:
6119584
分類程式碼代碼:
12352106
NACRES:
NA.25

品質等級

100

化驗

≥95% (GC)

光學活性

[α]/D 8.0±1.0°, c = 1 in H2O

儲存溫度

−20°C

InChI

1S/C6H12O4.Na/c1-6(2,3-7)4(8)5(9)10;/h4,7-8H,3H2,1-2H3,(H,9,10);/q;+1/p-1/t4-;/m0./s1

InChI 密鑰

XTIMSSMEPPKSQD-WCCKRBBISA-M

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生化／生理作用

(R)-泛解酸是磷酸泛酸生物合成途径中的中间体，在植物和微生物中用于由缬氨酸从头合成R-泛酸（维生素B5）。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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分析证书(COA)

Lot/Batch Number
BCCG7283
BCCF7517
BCCB9734
BCBZ6058
BCBW4135

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13C-NMR and 1H-1H NOEs of Coenzyme A: conformation of the pantoic acid moiety.
Dordine, R.L., et al.
Bioorganic Chemistry, 23, 169-181 (1995)
Analysis of stereochemistry of enzymically formed pantoyl lactone or pantoic acid by gas chromatography and circular dichroism.
D R Wilken et al.
Analytical biochemistry, 112(1), 9-16 (1981-03-15)
Hiroya Tomita et al.
Journal of bacteriology, 194(19), 5434-5443 (2012-08-07)
Although bacteria and eukaryotes share a pathway for coenzyme A (CoA) biosynthesis, we previously clarified that most archaea utilize a distinct pathway for the conversion of pantoate to 4'-phosphopantothenate. Whereas bacteria/eukaryotes use pantothenate synthetase and pantothenate kinase (PanK), the hyperthermophilic
Michael Rothmann et al.
Journal of the American Chemical Society, 135(16), 5962-5965 (2013-04-05)
Pantetheine and its corresponding disulfide pantethine play a key role in metabolism as building blocks of coenzyme A (CoA), an essential cofactor utilized in ~4% of primary metabolism and central to fatty acid, polyketide, and nonribosomal peptide synthases. Using a
Dayong Si et al.
Applied microbiology and biotechnology, 93(4), 1619-1625 (2011-11-16)
Ketopantoic acid (KPA) reductase catalyzes the stereospecific reduction of ketopantoic acid to D-pantoic acid. Based on the N-terminal amino acid sequence of KPA reductase from Stenotrophomonas maltophilia 845, the KPA reductase gene was cloned from S. maltophilia NBRC14161 and sequenced.

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