跳转至内容
Merck
所有图片(1)

Key Documents

SCC353

Sigma-Aldrich

3dGRO Sigmoid Colon Intestinal Organoids, Age 33 (Prep ht-205-CS)

登录查看公司和协议定价


About This Item

分類程式碼代碼:
41106509

包裝

vial of >1500 viable organoids cells

品質等級

製造商/商標名

Millipore

增長模式

N/A

技術

cell culture | mammalian: suitable

運輸包裝

liquid nitrogen

儲存溫度

−196°C

應用

  • Viability: >1500 viable organoids/vial
  • Organoid Growth: Pass
  • Cells are tested negative for infectious diseases by a Human Essential CLEAR panel by Charles River Animal Diagnostic Services.
  • Mycoplasma Contamination: Negative
  • STR Profile: Pass

Patient derived organoids (PDOs) are novel in vitro 3D cell models that preserve original tissue physiology and molecular pathology, thus representing a clinically-relevant alternative to traditional 2D cell lines and an effective tool to refine and reduce animal models. PDOs can be derived from adult patient biopsies or resected tissues containing native LGR5+ stem cell populations and cultured within an ECM-rich substrate using specialized organoid media such as L-WRN conditioned media. Adult tissue derived organoids are phenotypically and genetically stable in long term culture, presenting more mature phenotypes compared to iPSC-derived organoids. Importantly, PDOs have shown to be able to predict patient clinical responses to chemotherapeutics.

We are now offering a comprehensive biobank of highly characterized tissue-derived human gastrointestinal organoids from normal and diseased patients. The intestinal organoid biobank contains over 50 highly characterized intestinal organoids from both normal and diseased patients derived from multiple regions of the digestive systems including small intestine (duodenum, ileum), stomach, rectum and colon.

Cell Line Characteristics
  • Sex: Female
  • Age: 33 Years
  • Organ: Sigmoid Colon
  • Disease: Normal Margin to Crohns

特點和優勢

Cryopreserved patient derived gastrointestinal organoids (PDOs)

儲存和穩定性

Store in liquid nitrogen. The organoids can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.

其他說明

3dGRO is a trademark of Merck KGaA, Darmstadt, Germany.
3dGRO organoids were derived utilizing HUB Organoid Technology.
The purchaser of this product shall agree to HUB′s terms of use, which shall be separately acknowledged and accepted by such purchaser, prior to transfer of this product to purchaser.

免責聲明

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门