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Key Documents

MABN92-AF647

Sigma-Aldrich

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor 647 Conjugate

clone 20A12.1, from mouse, ALEXA FLUOR 647

别名:

Allograft inflammatory factor 1, AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.45

生物源

mouse

品質等級

共軛

ALEXA FLUOR 647

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

20A12.1, monoclonal

物種活性

mouse, human, rat

技術

immunofluorescence: suitable

同型

IgG1κ

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... AIF1(199)

一般說明

Allograft inflammatory factor 1 (UniProt P55008; also known as AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1) is encoded by the AIF1 (also known as G1, IBA1) gene (Gene ID 199) in human. Iba1/AIF1 is a 17 kDa interferon-gamma- (IFN-gamma-) inducible, Ca(2+)-binding EF-hand protein. Iba1/AIF1 expression is mostly limited to the macrophage/monocyte lineage, and is augmented by cytokines, such as IFN-gamma. It is reported to be involved in neuronal function, inflammatory responses, allograft rejection, autoimmunity, and macrophage activation/function. It is also shown to be expressed in microglial cells in autominnume disesase models such as experimental autoimmune encephalomyelitis, neuritis and uveitis.

應用

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor 647 Conjugate is an antibody against AIF1 for use in Immunofluorescence.
The unconjugated antibody (Cat. No. MABN92) is shown to be suitable also for Western blotting and immunohistochemistry applications.

品質

Evaluated by Immunofluorescence in human spleen tissue.

Immunofluorescence Analysis: A 1:50 dilution of this antibody detected Iba1/AIF1 in human spleen tissue.

標靶描述

~17 kDa observed.

其他說明

Concentration: Please refer to lot specific datasheet.

法律資訊

ALEXA FLUOR is a trademark of Life Technologies

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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