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Merck
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Key Documents

MABN356

Sigma-Aldrich

Anti-FKBP4 Antibody, clone 2H9.1

clone 2H9.1, from mouse

别名:

Peptidyl-prolyl cis-trans isomerase FKBP4, PPIase FKBP4, 51 kDa FK506-binding protein, FKBP51, 52 kDa FK506-binding protein, 52 kDa FKBP, FKBP-52, 59 kDa immunophilin, p59, FK506-binding protein 4, FKBP-4, FKBP59, HSP-binding immunophilin, HBI, Immunophi

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

2H9.1, monoclonal

物種活性

human

技術

immunohistochemistry: suitable (paraffin)
western blot: suitable

同型

IgG1κ

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... FKBP4(2288)

一般說明

FKBP4, also known as Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4), or 51 kDa FK506-binding protein (FKBP51), 52 kDa FK506-binding protein (FKBP-52), or 59 kDa immunophilin (p59), or FK506-binding protein 4 (FKBP-4) or FKBP59 , or HSP-binding immunophilin (HBI), or Immunophilin FKBP52 Rotamase, and encoded by the gene FKBP4/FKBP62 is a chaperon type protein that is involved in protein folding and trafficking and the immunoregulation of cellular responses. FKBP4 is a member of the immunophilin family of proteins. FKBP4 forms a component of unligated steroid receptors complexes and helps in the cycling of the receptors between the cytoplasm and nuclear compartments. FKBP4 also plays a role in regulating neuronal growth cones via the regulations of TRPC1 channels, and FKBP4 modules microtubule dynamics by inhibiting MAPT/TAU in microtubule assembly. Finally, FKBP4 also influences the regulation and modulation oxidative stress in mitochondria. FKBP4 will localize to the cytoplasm, mitochondria or nucleus depending upon cellular situation and is widely expressed.

免疫原

Epitope: C-terminus
GST-tagged recombinant protein corresponding to the C-terminus of human FKBP4.

應用

Anti-FKBP4 Antibody, clone 2H9.1 is an antibody against FKBP4 for use in western blotting & IHC (Paraffin).
Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected FKBP4 in human testis and human cerebellum tissue.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling

品質

Evaluated by Western Blotting in T47D cell lysate.

Western Blotting Analysis: 0.25 µg/mL of this antibody detected FKBP4 in 10 µg of T47D cell lysate.

標靶描述

~52 kDa observed

外觀

Protein G Purified
Format: Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1


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