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Merck
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主要文件

MABN2529

Sigma-Aldrich

Anti-HTT Antibody, clone MW8

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

抗體表格

purified antibody

無性繁殖

MW8
monoclonal

純化經由

using protein G

物種活性

mouse, mouse, human

濃度

(Please refer to lot specific datasheet.)

技術

ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG2aκ

UniProt登錄號

一般說明

HD exon-1 67Q aggregate.

特異性

Clone MW8 is a mouse monoclonal antibody that detects Huntingtin protein. It targets an epitope within nine amino acids in the exon-1 region.

應用

Immunocytochemistry Analysis: A representative lot detected HTT in Immunocytochemistry applications (Legleiter, J., et. al. (2009). J Biol Chem. 284(32):21647-58).

Immunohistochemistry Analysis: A representative lot detected HTT in Immunohistochemistry applications (Ko, J., et. al. (2001). Brain Res Bull. 56(3-4):319-29).

Western Blotting Analysis: A representative lot detected HTT in Western Blotting applications (Legleiter, J., et. al. (2009). J Biol Chem. 284(32):21647-58).

Enzyme Immunoassay (ELISA) Analysis: A representative lot detected HTT in ELISA applications (Ko, J., et. al. (2001). Brain Res Bull. 56(3-4):319-29).

Immunoprecipitation Analysis: A representative lot immunoprecipitated HTT in Immunoprecipitation applications (Baldo, B., et. al. (2012). Chem Biol. 19(2):264-75).

Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected HTT in Tissue lysate of 9 month-old WT or Q140 KI HD mice.

品質

Isotype testing: Identity Confirmation by Isotyping Test.

Isotyping Analysis: The identity of this monoclonal antibody is confirmed by isotyping test to be mouse IgG2a.

物理性質

347.6 kDa calclulated

外觀

Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

其他說明

Human, Mouse.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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