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Merck
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Key Documents

MABF846

Sigma-Aldrich

Anti-LAG3 Antibody, clone C9B7W (Azide Free)

别名:

LAG3|Lymphocyte activation gene 3 protein|LAG-3|CD223

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rat

品質等級

無性繁殖

monoclonal

物種活性

mouse

技術

activity assay: suitable
flow cytometry: suitable

一般說明

Lymphocyte-activation gene 3 (LAG3), also known as cluster of differentiation 223 (CD223), is an immunoglobulin superfamily (IgSF) type I membrane protein encoded by the LAG3 gene in human. LAG3 is expressed in human activated T and NK cells and involved lymphocyte activation by functioning as a ligand for major histocompatibility complex (MHC) class II molecules.

免疫原

Recombinant protein corresponding to within the extracellular D2 domain of mouse LAG3.

應用

Anti-LAG3 Antibody, clone C9B7W (Azide Free) is an antibody against LAG3 for use in Flow Cytometry, Activity Assay.
Flow Cytometry Analysis: A representative lot detected LAG3 in TILs from B16 and MC38 mice (Woo, S., et al. (2011). Cancer Research. 72(4):917-927).
Flow Cytometry Analysis: A representative lot detected LAG3 in activated T cells from CD223-/- and CD2

品質

Evaluated by Flow Cytometry in Staph enterotoxin B treated mouse splenocyte.

Flow Cytometry Analysis: 1.0 ug of this antibody detected LAG3 in Staph enterotoxin B treated mouse splenocyte.

其他說明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial

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