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Merck
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Key Documents

MABF155D

Sigma-Aldrich

Anti-CD44, (human/mouse), FITC, clone IM7 Antibody

clone IM7, from rat, FITC conjugate

别名:

CD44 antigen, Extracellular matrix receptor III (ECMR-III), GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Hermes antigen, Hyaluronate receptor, Lymphocyte antigen 24 (Ly-24), Phagocytic glycoprotein 1 (PGP-1), Phagocytic glycoprotein I (PGP-I), CD44

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.44

生物源

rat

品質等級

共軛

FITC conjugate

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

IM7, monoclonal

物種活性

mouse, human

包裝

antibody small pack of 25 μg

技術

flow cytometry: suitable

同型

IgG2bκ

UniProt登錄號

目標翻譯後修改

unmodified

基因資訊

human ... CD44(960)
mouse ... Cd44(12505)

一般說明

The IM7 antibody recognizes CD44, a ubiquitously expressed cell surface receptor which is important for extracellular matrix organization, cell-cell and cell-matrix adhesion and migration. CD44 may be expressed in a number of different isoforms (splice variants) from the most typical or “standard” form, known as CD44s, to variants designated CD44v, e.g. CD44v1 or CD44v6. These receptors interact with several ligands, but most often associate with an extracellular matrix component hyaluronate, through which it mediates adhesion.The IM7 antibody may be used for detection of all isoforms of CD44, as it recognizes constant epitopes near the extracellular proximal domain. (Xu et al, 2002, J. Leukoc. Biol. 72:1133-1141). It has been reported to be cross-reactive with many non-human species including Baboon, Chimpanzee, Cynomolgus, Rhesus, Horse, Cow, Pig, Dog and Cat CD44.

免疫原

Immunogen information for this antibody is proprietary information.

應用

Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
This rat monoclonal Anti-CD44 Antibody, (human/mouse), FITC, clone IM7, Cat. No. MABF1557 is validated for use in Flow Cytometry, for the detection of CD44.

品質

This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.5 μg from a representative lot detected CD44 in one million C57Bl/6 splenocytes.

外觀

Purified by size-exclusion chromatography
Purified Rat monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.
Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.

其他說明

Concentration: Please refer to lot specific datasheet.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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