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Merck
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Key Documents

MAB8051

Sigma-Aldrich

Anti-Adenovirus Antibody, clone 2/6

clone 2/6, Chemicon®, from mouse

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified immunoglobulin

無性繁殖

2/6, monoclonal

物種活性

human

製造商/商標名

Chemicon®

技術

ELISA: suitable
flow cytometry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable

同型

IgG1κ

運輸包裝

wet ice

一般說明

Adenoviruses are 65-80 nm, non-enveloped, regular icosahedron pathogens often associated with respiratory and gastrointestinal illness as well as conjunctivitis. Well over 40 types of adenoviruses have currently been recognized. In addition to their deleterious effects, adenoviruses have been used in vaccine production and in gene therapy. They also have the ability to trigger cell proliferation by interfering with host cellular anti-oncogenes. Since they are easy to prepare, multiple quickly and efficiently, and have the ability to infect and deliver their genome (including researcher-created constructs) to the nucleus of a variety of post-mitotic cells, adenoviruses are extremely valuable in research and medical applications ranging from virus/host cell interaction to the insertion of novel genes or regulatory mechanisms into eukaryotic cellular systems, to delivery of therapeutic anti-cancer genes.

特異性

All 41 serotypes of Adenovirus.

應用

Detect Adenovirus using this Anti-Adenovirus Antibody, clone 2/6 validated for use in ELISA, FC, IF, IH.
ELISA

IFA: acetone fixed cell preparations or tissues.

FACS: {McNees, 2004}

Dilute with buffer pH 7.5-8.0 to desired working volume.

For extensive dilution, protein containing or other stabilizing medium should be used.

Final working dilutions must be determined by end user.

外觀

Format: Purified
Protein A-purified immunoglobulin. Liquid at 1 mg/mL in 20 mM phosphate buffer, containing 25 mM NaCl and 0.1% sodium azide, pH 7.6

儲存和穩定性

Maintain at 2-8°C in convenient aliquots for up to 12 months. Do not store in a diluted format.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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An outbreak of epidemic keratoconjunctivitis in a regional ophthalmology clinic in New South Wales.
K A Viney,P J Kehoe,B Doyle,V Sheppeard,A R Roberts-Witteveen,H Semirli,K A McPhie et al.
Epidemiology and Infection null
Modeling adenovirus latency in human lymphocyte cell lines.
Zhang, Y; Huang, W; Ornelles, DA; Gooding, LR
Journal of virology null
Protein crystals in Adenovirus type 5-infected cells: requirements for intranuclear crystallogenesis, structural and functional analysis.
Franqueville, L; Henning, P; Magnusson, M; Vigne, E; Schoehn, G; Blair-Zajdel, ME; Habib et al.
Testing null
Postinternalization inhibition of adenovirus gene expression and infectious virus production in human T-cell lines.
McNees, AL; Mahr, JA; Ornelles, D; Gooding, LR
Journal of virology null

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