推荐产品
生物源
mouse
品質等級
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
27/21, monoclonal
物種活性
human, rat, mouse, bovine
製造商／商標名
Chemicon®
技術
ELISA: suitable
同型
IgG1
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... NTF3(4908)
特異性
NGF is a neurotrophic protein which is synthesized by the target tissues of NGF-sensitive neurons. NGF acts on sympathetic and sensoric neurons as well as on cholinergic neurons of the basal forebrain. It has been suggested that NGF is involved in the neuropathology of Alzheimer′s Disease (Hefti & Weiner, 1986). In the peripheral nervous system, NGF plays a role in the development of autonomic and sensory neuropathies (Anand et al., 1991).
The antibody specifically reacts with the beta -subunit of NGF from mouse, in the 2.5S- as well as in the 7S-form.
The cross-reactivity with human NGF is 60-90 % of the reactivity with mouse NGF
The antibody specifically reacts with the beta -subunit of NGF from mouse, in the 2.5S- as well as in the 7S-form.
The cross-reactivity with human NGF is 60-90 % of the reactivity with mouse NGF
免疫原
2.5 S form of mouse NGF.
應用
ELISA
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins
Neurochemistry & Neurotrophins
This Anti-Nerve Growth Factor Antibody, clone 27/21 is validated for use in ELISA for the detection of Nerve Growth Factor.
外觀
Format: Purified
Purified immunoglobulin. Lyophilized from 0.02M Phosphate buffer, 0.25M NaCl with 0.1% sodium azide. Reconstitute with 1 mL of sterile distilled water.
儲存和穩定性
The lyophilized antibody is stable if stored dry at 2-8°C for up to 12 months. After reconstitution maintain at 4°C unaliquotted but sealed tightly for 6 months; do not freeze thaw.
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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訊號詞
Danger
危險分類
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
New autonomic and sensory neuropathy with loss of adrenergic sympathetic function and sensory neuropeptides.
Anand, P, et al.
Lancet, 337, 1253-1254 (1991)
Nerve growth factor: mechanism of action.
Vinores, S and Guroff, G
Annual Review of Biophysics and Bioengineering, 9, 223-257 (1980)
Deoxyribonucleic acids and related compounds. XXII. Synthesis of genes for human nerve growth factor and its fused protein.
Iwai, S, et al.
Chemical & Pharmaceutical Bulletin, 34, 4724-4730 (1986)
Nerve growth factor (NGF) is present in human placenta and semen, but undetectable in normal and Paget's disease blood: measurements with an anti-mouse-NGF enzyme immunoassay using a recombinant human NGF reference.
Heinrich, G and Meyer, T E
Biochemical and biophysical research communications, 155, 482-486 (1988)
L Velasco et al.
European journal of biochemistry, 268(3), 531-535 (2001-02-13)
Cannabinoids, the active components of marihuana, exert a variety of effects in humans. Many of these effects are mediated by binding to two types of cannabinoid receptor, CB1 and CB2. Although CB1 is located mainly in the central nervous system
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