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Key Documents

MAB2120Z

Sigma-Aldrich

Anti-NCAM Antibody, extracellular, clone ERIC-1, Azide free

clone ERIC-1, Chemicon®, from mouse

别名:

NeuralCellAdhesionMolecule, CD56, MAB2120

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

ERIC-1, monoclonal

物種活性

human, pig

製造商/商標名

Chemicon®

技術

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

同型

IgG1

適合性

not suitable for flow cytometry

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... NCAM1(4684)

一般說明

The previously assigned protein identifier P13592 has been merged into P13591. Full details can be found on the UniProt database.

特異性

Recognizes N-CAM expressed on developing and adult neuroectrodermal tissues in Humans. Neuroectodermal tumors also stain including Elioma, ependymoma, neuroblastoma, medulloblastoma, retinoblastoma and teratoma. Oat cell carcinoma and Wilms tumor are also highly reactive. Will react on Natural Killer cells. Recognizes 120, 140 and 180 kDa NCAM isoforms.

免疫原

Epitope: extracellular
Human Retinoblastoma tumor

應用

Anti-NCAM Antibody, extracellular, clone ERIC-1, Azide free is an antibody against NCAM for use in ELISA, WB, IH.
Immunohistology on frozen tissue sections acetone fixation only.

Immunoblotting: Recognizes 120, 140, and 180 kDa NCAM isoforms.

ELISA: 80 ng/mL

Does not work in flow cytometry.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Growth Cones & Axon Guidance

Neurofilament & Neuron Metabolism

聯結

Replaces: MAB2122

外觀

Format: Purified
Liquid in PBS. Does not contain any preservatives

儲存和穩定性

Store at -20°C only. Avoid repeated freeze-thaw cycles.

分析報告

Control
Recommended positive control tissue: Neuroblastoma

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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GDNF family ligands trigger indirect neuroprotective signaling in retinal glial cells.
Hauck, SM; Kinkl, N; Deeg, CA; Swiatek-de Lange, M; Schoffmann, S; Ueffing, M
Molecular and cellular biology null
Priyadarsini Kumar et al.
PloS one, 10(8), e0135089-e0135089 (2015-08-13)
Trophoblast differentiation during early placental development is critical for successful pregnancy and aberrant differentiation causes preeclampsia and early pregnancy loss. During the first trimester, cytotrophoblasts are exposed to low oxygen tension (equivalent to~2%-3% O2) and differentiation proceeds along an extravillous

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