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HCVD6MAG-67K

Millipore

MILLIPLEX® Human Cardiovascular Disease Magnetic Bead Panel 6 - Cardiovascular Disease (CVD) Multiplex Assay

The analytes available for this multiplex kit are: sCD14, DPP4/sCD26, Endostatin, pGRN, LRG1, MCAM, ucMGP

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About This Item

分類程式碼代碼:
12161503
eCl@ss:
32161000
NACRES:
NA.47

品質等級

物種活性

human

製造商/商標名

Milliplex®

assay range

accuracy: 92%
(Endostatin)

accuracy: 95%
(ucMGP)

accuracy: 97%
(DPP4/sCD26)

sensitivity: 0.007 ng/mL
(MinDC+2SD; Endostatin)

sensitivity: 0.014 ng/mL
(MinDC+2SD; pGRN)

sensitivity: 0.015 ng/mL
(MinDC+2SD; LRG1)

sensitivity: 0.016 ng/mL
(MinDC+2SD; MCAM)

sensitivity: 0.016 ng/mL
(MinDC+2SD; sCD14)

sensitivity: 0.041 ng/mL
(MinDC+2SD; DPP4)

sensitivity: 0.052 ng/mL
(MinDC+2SD; ucMGP)

standard curve range: 0.002-10 ng/mL
(Endostatin)

standard curve range: 0.01-40 ng/mL
(sCD14)

standard curve range: 0.024-100 ng/mL
(LRG1)

standard curve range: 0.024-100 ng/mL
(MCAM)

standard curve range: 0.024-100 ng/mL
(pGRN)

standard curve range: 0.049-200 ng/mL
(DPP4/sCD26)

standard curve range: 0.049-200 ng/mL
(ucMGP)

inter-assay cv: <10%
intra-assay cv: <5%
(DPP4/sCD26)

inter-assay cv: <10%
intra-assay cv: <5%
(Endostatin)

inter-assay cv: <10%
intra-assay cv: <5%
(LRG1)

inter-assay cv: <10%
intra-assay cv: <5%
(MCAM)

inter-assay cv: <10%
intra-assay cv: <5%
(pGRN)

inter-assay cv: <20%
intra-assay cv: <10%
(ucMGP)

inter-assay cv: <20%
intra-assay cv: <5%
(sCD14)

技術

multiplexing: suitable

檢測方法

fluorometric (Luminex xMAP)

運輸包裝

ambient

一般說明

Cardiovascular disease is one of the major causes of death worldwide. Assessing the risk for cardiovascular disease is an important aspect in clinical decision making and setting a therapeutic strategy. The use of serological biomarkers may significantly facilitate risk factor identification. By exploring new applications of established biomarkers and new approaches to identify novel biomarkers, researchers continue to refine the mechanistic understanding of the biology of CVD diseases.

The MILLIPLEX® Human Cardiovascular Disease (CVD) Panel 6 is a 7-plex kit may be used to simultaneously quantify any or all the following analytes in human serum, plasma, and tissue culture samples: Soluble Cluster of Differentiation 14 (sCD14), Dipeptidyl Peptidase-4 (DPP4/DPPIV) / Soluble Cluster of Differentiation 26 (sCD26), Endostatin / Collagen Alpha-1 (XVIII) (COL181A), Progranulin (pGRN) / Proepithelin (PEPI) / PC Cell-derived Growth Factor (PCDGF) / Acrogranin / Paragranulin, Leucine-rich Alpha-2-Glycoprotein 1 (LRG1), Melanoma Cell Adhesion Molecule (MCAM) / Soluble Cluster of Differentiation 146 (sCD146) / Cell Surface Glycoprotein MUC18, Uncarboxylated Matrix Gamma-Carboxyglutamate (Gla) Protein (ucMGP). This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Cardiovascular

特異性

Cross Reactivty
There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

應用

  • Analytes: Monocyte Differentiation Antigen (CD14/sCD14), Dipeptidyl Peptidase-4 (DPP4/sCD26), Endostatin, Leucine-rich α-2-glycoprotein 1 (LRG1), Cell Surface Glycoprotein (MCAM/ MUC18/sCD146), Progranulin (pGRN), Uncarboxylated Matrix Gla Protein (ucMGP)
  • Recommended Sample Type:
  • Human serum, plasma, cell/tissue culture supernatants and lysates
  • Recommended Sample Dilution: 25 μL per well of 1:500 diluted serum or plasma; cell/tissue culture supernatants or lysates may be used undiluted ore or diluted in appropriate control medium
  • Assay Run Time: Overnight (16-18 hours)at 2-8°C will yield optimal sensitivity.2- A 2 hour incubation at room temperature (20-25°C) may also be used.
  • Research Category: Cardiovascular Disease
  • Research Subcategory: Metabolic Disorders

特點和優勢

Design your multiplex kit by choosing available analytes within this panel.

包裝

Everything you need in a single kit.

儲存和穩定性

Recommended storage for kit components is 2 - 8°C.

其他說明

Please contact Technical Service for linearity of dilution.

法律資訊

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

訊號詞

Danger

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

標靶器官

Respiratory Tract

儲存類別代碼

10 - Combustible liquids


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相关内容

Learn about biomarkers of cardiovascular disease (CVD) and discover how multiplex CVD panels, such as MILLIPLEX® multiplex assays, are being used to increase the efficiency of biomarker discovery for CVD research.

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