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Merck
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Key Documents

FCMAB182F

Sigma-Aldrich

Milli-Mark® Anti-CD15-FITC Antibody, clone C3D-1

clone C3D-1, Milli-Mark®, from mouse

别名:

Alpha-(1,3)-fucosyltransferase, Galactoside 3-L-fucosyltransferase, Fucosyltransferase 4, Fucosyltransferase IV, FucT-IV, Fuc-TIV, ELAM-1 ligand fucosyltransferase

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.44

生物源

mouse

品質等級

共軛

FITC conjugate

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

C3D-1, monoclonal

物種活性

human

製造商/商標名

Milli-Mark®

技術

flow cytometry: suitable

同型

IgMκ

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... FUT4(2526)

一般說明

CD15 is a carbohydrate antigen carried by both glycoproteins and glycoliplds. The structure of the antigen was determined to be Galb1→4[Fuca1→3]GIcNACb1→3Galb1→R. CD15 serves as a ligand for selectins and might also be involved in cell adhesion through a direct Lewis X-Lewis X interaction. CD15 is expressed mainly on mature granulocytes and monocytes but also on immature bone marrow cells (Kannagi, 1997).
Anti-CD15, C3D-1, was included in the Sixth International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with CD15 (Kannagi, 1997).

特異性

Antibody recognizes Human CD15 antigen.

免疫原

Purified human neutrophils

應用

This Milli-Mark Anti-CD15-FITC Antibody, clone C3D-1 is validated for use in FC for the detection of CD15.

品質

Evaluated by flow cytometry using human PBMCs

外觀

Activated Sepharose
Purified Mouse monoclonal IgM conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Marlieke L M Jongsma et al.
Immunity, 54(1), 132-150 (2020-12-04)
HLA class I (HLA-I) glycoproteins drive immune responses by presenting antigens to cognate CD8+ T cells. This process is often hijacked by tumors and pathogens for immune evasion. Because options for restoring HLA-I antigen presentation are limited, we aimed to identify

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