ABS811
Anti-FABP7 Antibody
from rabbit, purified by affinity chromatography
别名:
Fatty acid-binding protein, brain, Brain lipid-binding protein, BLBP, Brain-type fatty acid-binding protein, B-FABP, Fatty acid-binding protein 7, Mammary-derived growth inhibitor related, FABP7
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所有图片(2)
About This Item
分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41
推荐产品
生物源
rabbit
品質等級
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
純化經由
affinity chromatography
物種活性
human
技術
immunohistochemistry: suitable
western blot: suitable
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... FABP7(2173)
一般說明
FABP7 is a member of the large family of hydrophobic ligand-binding proteins (FABPs). FABP proteins are involved in lipid metabolism, including uptake and intracellular trafficking of fatty acids and retinoids. In addition, they play a role in gene regulation, cell signaling, cell growth and differentiation. Several reports have suggested a possible role for the different FABP proteins in cancer biology, linking their levels with either increasing or decreasing the degree of malignancy. Nine FABPs (FABP1-FABP9) have been identified. FABP7 is a brain-specific protein that is required for the establishment of the radial glial fiber system in the developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers. It is expressed at high levels in the developing central nervous system. FABP7 has also been found in melanocytic lesions and has shown to regulate proliferation and invasion in melanoma cells in vitro, suggesting that it may play a role in cell proliferation and invasion.
免疫原
Epitope: Near Center
FABP7 antibody was raised against a 17 amino acid synthetic peptide from near the center of human FABP7.
應用
Immunohistochemistry Analysis (IHC): 5 μg/mL from a representative lot detected FABP7 in human breast tissue.
Research Category
Signaling
Signaling
Research Sub Category
Developmental Signaling
Developmental Signaling
This Anti-FABP7 Antibody is validated for use in Western Blotting_x000D_ and Immunohistochemistry for the detection of FABP7.
品質
Evaluated by Western Blotting in human breast tissue lysate.
Western Blotting Analysis (WB): 1 μg/mL of this antibody detected FABP7 in human breast tissue lysate.
Western Blotting Analysis (WB): 1 μg/mL of this antibody detected FABP7 in human breast tissue lysate.
標靶描述
~24 kDa observed. Uncharacterized bands may be observed in some lysate(s).
聯結
Replaces: MABS184
外觀
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.
儲存和穩定性
Stable for 1 year at 2-8°C from date of receipt.
其他說明
Concentration: Please refer to lot specific datasheet.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Nolwenn Pasquet et al.
Cerebral cortex (New York, N.Y. : 1991), 29(6), 2482-2498 (2018-06-08)
Modifications of neuronal migration during development, including processes that control cortical lamination are associated with functional deficits at adult stage. Here, we report for the first time that the lack of the serine protease tissue-type Plasminogen Activator (tPA), previously characterized
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