ABS190

Anti-PIP5K-Type 1 gamma Antibody

from rabbit

• 别名: Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma, PIP5K1-gamma, PtdIns(4)P-5-kinase 1 gamma, Phosphatidylinositol 4-phosphate 5-kinase type I gamma, PIP5KIgamma
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物源: rabbit
• 抗體表格: purified antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 物種活性: rat, mouse
• 技術: immunohistochemistry: suitable; western blot: suitable
• 同型: IgG1
• NCBI登錄號: NP_001140159
• UniProt登錄號: O70161
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: mouse ... Pip5K1C(18717)

说明

一般說明

Phosphatidylinositol-4-phosphate 5-kinase 1 gamma (PIP5K type 1 gamma; PIP5K1γ) is a ubiquitous protein which is enriched in focal adhesion plaques. It is expressed in relatively high levels in the brain, particularly at synaptic sites. PIP5K type 1 gamma is activated by talin, and in turn phosphorylates phosphatidylinositol 4-phosphate to form phosphatidylinositol 4,5-bisphosphate, the precursor to the second messenger phosphatidylinositol 3,4,5-trisphosphate. It indirectly influences vesicle transport, cell adhesion, and cell migration, among other processes. Defects in PIP5K type 1 gamma may contribute to lethal congenital arthrogryposis.

免疫原

recombinant protein corresponding to mouse PIP5K-type 1 gamma.

應用

Anti-PIP5K-Type 1 gamma Antibody detects level of PIP5K-Type 1 gamma & has been published & validated for use in Western Blotting & IHC.

Immunohistochemistry Analysis: A representative lot from an independent laboratory detected PIP5K-Type 1 gamma in rat brain tissues (Wenk, M. R., et al. 2001. Neuron. 32(1):79-88.).

Research Category
Signaling

Research Sub Category
Cytoskeletal Signaling

品質

Evaluated by Western Blot in mouse brain tissue lysate.

Western Blot Analysis: 1 mg/mL of this antibody detected PIP5K-Type 1 gamma in 10 mg of mouse brain tissue lysate.

標靶描述

~90 kDa observed. The calculated molecular weight of PIP5K Type-1 gamma is 69-72 kDa, but has been observed at ~90 kDa in Western Blot (Volpicelli-Daley, L.A., et al. (2010). 285(37):28708-28714.).

外觀

Protein A purified

Format: Purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
Mouse brain tissue lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.