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Key Documents

AB9210

Sigma-Aldrich

抗胰岛素降解酶抗体

serum, Chemicon®

别名:

IDE, Insulysin, Insulinase

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

serum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

rat

包裝

antibody small pack of 25 μL

製造商/商標名

Chemicon®

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

rat ... Ins1(24505)

特異性

胰岛素降解酶(IDE)。 由于免疫原序列同源性,预计该抗体也与人和小鼠反应。

免疫原

来自大鼠 IDE 的合成肽。

應用

抗胰岛素降解酶抗体是针对胰岛素降解酶的抗体,用于 WB。
研究子类别
神经退行性疾病
研究类别
神经科学
蛋白质印迹:1:10,000-1:20,000.该抗体识别大鼠肝组织裂解液中约 110 kDa 的蛋白质。

最佳工作稀释度必须由最终用户确定。

品質

经过测试

外觀

兔血清。 液体。

儲存和穩定性

自收到之日起,在 -20°C 以未稀释的等分试样可保存 6 个月。应避免反复冻/融循环。

其他說明

请参考特定批次的数据表。

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Miriam Corraliza-Gómez et al.
Cells, 11(2) (2022-01-22)
The insulin-degrading enzyme (IDE) is a zinc-dependent metalloendopeptidase that belongs to the M16A metalloprotease family. IDE is markedly expressed in the brain, where it is particularly relevant due to its in vitro amyloid beta (Aβ)-degrading activity. The subcellular localization of
Carlos M González-Casimiro et al.
Cells, 10(9) (2021-09-29)
Insulin-degrading enzyme (IDE) is a highly conserved and ubiquitously expressed Zn2+-metallopeptidase that regulates hepatic insulin sensitivity, albeit its regulation in response to the fasting-to-postprandial transition is poorly understood. In this work, we studied the regulation of IDE mRNA and protein
Yan-Xi Chen et al.
Nutrients, 13(12) (2021-12-29)
Declines in physiological functions are the predominant risk factors for age-related diseases, such as cancers and neurodegenerative diseases. Therefore, delaying the aging process is believed to be beneficial in preventing the onset of age-related diseases. Previous studies have demonstrated that
Abhay P Sagare et al.
Nature communications, 4, 2932-2932 (2013-12-18)
Pericytes are cells in the blood-brain barrier that degenerate in Alzheimer's disease (AD), a neurological disorder associated with neurovascular dysfunction, abnormal elevation of amyloid β-peptide (Aβ), tau pathology and neuronal loss. Whether pericyte degeneration can influence AD-like neurodegeneration and contribute
Tsai-Teng Tzeng et al.
International journal of molecular sciences, 19(2) (2018-02-22)
Hericium erinaceus was used in traditional Chinese medicine for physiologically beneficial medicines. Recently, it has become a candidate in causing positive brain health-related activities. We previously reported that Hericium erinaceus mycelium ameliorates Alzheimer's disease (AD)-related pathologies. To reveal the role

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