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Merck
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Key Documents

AB1690

Sigma-Aldrich

Anti-Ubiquitin Antibody

serum, Chemicon®

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

serum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

bovine, eukaryotes, human

製造商/商標名

Chemicon®

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... UBAP2(55833)

特異性

Ubiquitin (76 amino acid, 8.5 kDa). Shows staining of neurofibrillary tangles, neurites in senile plaques and a subset of neuronal processes. No reactivity seen to tau, neurofilament or microtubule-associated proteins.

免疫原

Purified uboquitin covalently coupled to KLH using glutaraldehde.

應用

Anti-Ubiquitin Antibody detects level of Ubiquitin & has been published & validated for use in WB, IH, IH(P).
Immunohistochemistry: 1:1,000-1:5,000. Tissue fixed in 10% formalin, Bouin′s fixative for 1-2 days and embedded in paraffin, or unfixed frozen tissues may be used.

Immunoblotting: 1:1,000-1:5,000.

Optimal working dilutions must be determined by end user.
Research Category
Protein Trafficking
Research Sub Category
Ubiquitin & Ubiquitin Metabolism

外觀

Neat rabbit antisera with 10 mM sodium azide.

儲存和穩定性

Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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Identification of Salmonella Typhimurium Deubiquitinase SseL Substrates by Immunoaffinity Enrichment and Quantitative Proteomic Analysis.
Nakayasu, ES; Sydor, MA; Brown, RN; Sontag, RL; Sobreira, TJ; Slysz, GW; Humphrys et al.
Journal of Proteome Research null
Jackalina M Van Kampen
Methods in molecular biology (Clifton, N.J.), 1806, 255-267 (2018-06-30)
Progranulin (PGRN) is a multifunctional protein that is widely expressed throughout the brain, where it has been shown to be a critical regulator of CNS inflammation (Ahmed et al., J Neuroinflammation 4:7, 2007; Yin et al., J Exp Med 207:117-128
Nataša Bauer et al.
Frontiers in plant science, 10, 1469-1469 (2019-12-12)
MATH-BTB proteins are known to act as substrate-specific adaptors of CUL3-based E3 ligases in the ubiquitin proteasome pathway. Their BTB domain binds to CUL3 scaffold proteins and the less conserved MATH domain targets a highly diverse collection of substrate proteins
Intracellular retention, degradation, and signaling of glycosylation-deficient FGFR2 and craniosynostosis syndrome-associated FGFR2C278F.
Hatch, NE; Hudson, M; Seto, ML; Cunningham, ML; Bothwell, M
The Journal of Biological Chemistry null
Sperm proteasomes degrade sperm receptor on the egg zona pellucida during mammalian fertilization.
Zimmerman, SW; Manandhar, G; Yi, YJ; Gupta, SK; Sutovsky, M; Odhiambo, JF; Powell et al.
Testing null

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