AB16530

Anti-BAFF Antibody, CT

Chemicon^®, from rabbit

• 别名: TALL-1, THANK, BLyS
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 物種活性: rat, human, mouse
• 製造商／商標名: Chemicon^®
• 技術: western blot: suitable
• NCBI登錄號: NM_006573.3
• UniProt登錄號: Q9Y275
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... TNFSF13B(10673) ; mouse ... Tnfsf13B(24099) ; rat ... Tnfsf13B(498666)

说明

特異性

Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF (for B cell Activating Factor belonging to the TNF Family), BlyS (for B Lymphocyte Stimulator), TALL-1 (for TNF- and ApoL-related Leukocyte-expressed Ligand), and THANK (for TNF Homologue that Activate Apoptosis, NF-kB and c-jun N-terminal kinase) (Moore et al. 1999; Schneider et al. 1999; Shu et al. 1999; Mukhopadhyay et al. 1999). BAFF/BlyS was characterized as a B cell stimulator since it induced B cell proliferation and immunoglobulin secretion (Moore et al. 1999; Schneider et al. 1999). Two receptors for BAFF were recently identified and designated TACI and BCMA (Gross et al. 2000). BAFF and its receptors are involved in the development of systemic lupus erythaematosus and other B cell associated autoimmune diseases (Gross et al. 2000; Khare et al. 2000). Like TNFalpha and TRAIL, THANK was shown to activate NF-kB and c-jun N-terminal kinase (JNK) and to induce apoptosis (Mukhopadhyay et al. 1999).

免疫原

Epitope: C-terminus

Rabbit anti-BAFF (C-term) polyclonal antibody was raised against a peptide corresponding to amino acids 254 to 269 of human BAFF (Moore et al. 1999; Schneider et al. 1999; Shu et al. 1999; Mukhopadhyay et al. 1999).

應用

Anti-BAFF Antibody, C-terminus detects level of BAFF & has been published & validated for use in WB.

Research Category
Apoptosis & Cancer

Research Sub Category
BCL2 & Inhibition

Western blot: 0.25 to 1 μg/mL.

Optimal working dilutions must be determined by end user.

外觀

Format: Purified

Purified immunoglobulin. Liquid in PBS containing 0.02% sodium azide.

儲存和穩定性

Maintain at 2-8°C in undiluted aliquots for up to 12 months.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable