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Merck
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Key Documents

8.55043

Sigma-Aldrich

IBX polystyrene

Novabiochem®

别名:

Polystyrene-Bound IBX

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About This Item

分類程式碼代碼:
13111023
NACRES:
NA.22

品質等級

產品線

Novabiochem®

形狀

beads

反應適用性

reaction type: solution phase peptide synthesis
reactivity: alcohol reactive

製造商/商標名

Novabiochem®

應用

peptide synthesis

儲存溫度

2-8°C

一般說明

This polymer-bound version of IBX cleanly converts primary and secondary alcohols to the corresponding aldehydes and ketones [1,2]. It is particularly useful for the synthesis of peptide aldehydes as it oxidises peptide alcohols efficiently and spent resin can be simply removed by filtration.

Literature references

[1] G. Sorg, et al. (2001) Angew. Chem. Int. Ed., 40, 4395.
[2] G. Sorg, et al. (2005) J. Pept. Sci.,11, 147.

應用

  • 2-Iodoxybenzoic Acid: An Oxidant for Functional Group Transformations: This study discusses the use of IBX for various organic transformations, including the oxidation of silyl enol ethers and the preparation of polystyrene supported periodinane reagent. (Nair, 2020).

聯結

Replaces: 01-64-0445

分析報告

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined by elemental analysis of iodine): 0.90 - 1.50 mmol/g
Oxidation of Cinnamyl alcohol to Cinnamaldehyde (2 eq. IBX PS): ≥ 90 %
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly (styrene - 1% DVB) 200 -400 mesh.

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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