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Merck
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Key Documents

8.41359

Sigma-Aldrich

Triisopropylsilane

for synthesis

别名:

Triisopropylsilane

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About This Item

线性分子式:
((CH3)2CH)3SiH
CAS号:
分子量:
158.36
MDL號碼:
分類程式碼代碼:
12352103

品質等級

化驗

≥98.0% (GC)

形狀

liquid

bp

84-85 °C/46.7 hPa

轉變溫度

flash point 35 °C

密度

0.77 g/cm3 at 20 °C

儲存溫度

2-30°C

InChI

1S/C9H22Si/c1-7(2)10(8(3)4)9(5)6/h7-10H,1-6H3

InChI 密鑰

YDJXDYKQMRNUSA-UHFFFAOYSA-N

應用

  • Total synthesis of diazaquinomycins H and J using double Knorr cyclization: This paper covers the first total synthesis of diazaquinomycins, highlighting the role of triisopropylsilane in enhancing reaction efficiency (Prior & Sun, 2019).
  • Reduction of cysteine‐S‐protecting groups by triisopropylsilane: An in-depth look at the chemical properties of triisopropylsilane, emphasizing its effectiveness in peptide synthesis processes (Ste. Marie & Hondal, 2018).

分析報告

Assay (GC, area%): ≥ 98.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.765 - 0.772
Identity (IR): passes test

象形圖

Flame

訊號詞

Warning

危險聲明

危險分類

Flam. Liq. 3

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

100.4 °F - closed cup

閃點(°C)

38 °C - closed cup


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Fmoc resin cleavage and deprotection follows the difficult task of detaching the peptide from the resin support and removing all the side-chain protecting groups of the amino acid residues to yield the desired peptide.

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