8.02301

1,1′-羰基二咪唑

for synthesis

• 别名: 1,1′-羰基二咪唑
• 经验公式（希尔记法）: C₇H₆N₄O
• CAS号: 530-62-1
• 分子量: 162.15
• MDL號碼: MFCD00005286
• 分類程式碼代碼: 12352115
• 酶委員會索引編號: 208-488-9
• NACRES: NA.22

属性

• 品質等級: 200
• 化驗: ≥97.0% (GC)
• 形狀: powder
• 效力: 1071 mg/kg LD₅₀, oral (Rat)
• 反應適用性: reaction type: Carbonylations
• pH值: 7.7 (20 °C, 50 g/L in H₂O)
• mp: 116-120 °C
• 應用: peptide synthesis
• 儲存溫度: 2-8°C
• InChI: 1S/C7H6N4O/c12-7(10-3-1-8-5-10)11-4-2-9-6-11/h1-6H
• InChI 密鑰: PFKFTWBEEFSNDU-UHFFFAOYSA-N

说明

應用

• Facile Synthesis of 2-(1H-indol-3-yl)-acetamides: Synthesizing acetamides using 1,1′-Carbonyldiimidazole, showcasing its role in forming a reactive intermediate with pyridine (KMK Kanwal, B Fatima, B Bano, U Salar - J. Chem. Soc. Pak, 2016).


• Nanoflower Enhanced Capacitive Aptasensor: The synthesis of a novel hybrid nanoflower using 1,1′-Carbonyldiimidazole for attomolar detection limits in milk contamination detection (IG Subramani, V Perumal, SCB Gopinath - Scientific Reports, 2021).


• Thermodynamic Properties Analysis: The data on the thermodynamic properties of 1,1′-Carbonyldiimidazole and its applications in understanding material behaviors (JB Campos, JM Toro Jauregui - Journal of the Mexican Chemical Society, 2020).


• Synthesis of Deuterated Triacylglycerides: The use of 1,1′-Carbonyldiimidazole in the synthesis of medium chain triglyceride oil, highlighting its application in food emulsion studies (K Schwärzer, T Heiden‐Hecht, Y Chen - European Journal of Organic Chemistry, 2023).


• Mechanochemical Carbamate Synthesis: The use of 1,1′-Carbonyldiimidazole in an eco-friendly synthesis of carbamates, demonstrating its versatility as an acyl transfer reagent (M Lanzillotto, L Konnert, F Lamaty - ACS Sustainable Chemistry & Engineering, 2015).

分析報告

含量（GC，area%）： ≥ 97.0％（a/a）
熔化范围（较低值）： ≥ 115 °C
熔程（上限值）： ≤ 121 °C
鉴别（IR）：符合检验

安全信息

• 象形圖: GHS05,GHS07
• 訊號詞: Danger
• 危險聲明: H302 - H314
• 防範說明: P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
• 儲存類別代碼: 8A - Combustible, corrosive hazardous materials
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable