539522

PKC_ε Translocation Inhibitor Peptide

The PKC_ε Translocation Inhibitor Peptide, Negative Control controls the biological activity of PKC_ε. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

• 别名: PKC_ε Translocation Inhibitor Peptide, Protein Kinase Cε Translocation Inhibitor I, EAVSLKPT, PKCε Translocation Inhibitor I, PKCε-RACK2 Interaction Inhibitor I
• 经验公式（希尔记法）: C₃₇H₆₅N₉O₁₃
• 分子量: 843.96
• 分類程式碼代碼: 12352202
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥97% (HPLC)
• 形狀: lyophilized solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; desiccated (hygroscopic)
• 顏色: white
• 溶解度: water: 3 mg/mL
• 運輸包裝: ambient
• 儲存溫度: 2-8°C

说明

一般說明

An octapeptide that selectively inhibits the translocation of protein kinase C_ε to subcellular sites in a reversible manner. Inhibition of PKC_ε translocation is known to specifically block phorbol ester- or norepinephrine-mediated regulation of contraction in cardiomyocytes.

生化／生理作用

Cell permeable: no

Primary Target
PKCε Translocation

Product does not compete with ATP.

Reversible: yes

警告

Toxicity: Standard Handling (A)

序列

H-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH

外觀

Supplied as a trifluoroacetate salt.

重構

Following reconstitution, aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 6 months at -20°C.

其他說明

Yedovitzky, M., et al. 1997. J. Biol. Chem. 272, 1417.
Johnson, J.A., et al. 1996. J. Biol. Chem.271, 24962.

法律資訊

Sold under license of U.S. Patent 5,783,405.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable