5.05878

PD 168077 Maleate

• 别名: PD 168077 Maleate, D₄ Dopamine Receptor Agonist, PD 168077 Maleate, PD168077, PD-168077
• 经验公式（希尔记法）: C₂₀H₂₂N₄O · xC₄H₄O₄
• CAS号: 630117-19-0
• 分子量: 334.41 (free base basis)
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 化驗: ≥98% (HPLC)
• 品質等級: 100
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; protect from light
• 顏色: white
• 溶解度: DMSO: 100 mM
• 儲存溫度: −20°C
• InChI: 1S/C20H22N4O.C4H4O4/c1-16-5-4-7-17(13-16)20(25)22-15-23-9-11-24(12-10-23)19-8-3-2-6-18(19)14-21;5-3(6)1-2-4(7)8/h2-8,13H,9-12,15H2,1H3,(H,22,25);1-2H,(H,5,6)(H,7,8)/b;2-1-
• InChI 密鑰: NAEUGRPISCANHO-BTJKTKAUSA-N

说明

一般說明

A selective D₄ dopamine receptor agonist (K_i = 8.7 nM, EC₅₀ = 8.3 nM). Suitable for central and peripheral delivery. Used in studies of penile erection, learning and memory. Exibits some binding affinity towards human D₂ and D₃ Receptors (K_i = 2.8 µM).

生化／生理作用

Primary Target
D₄

Reversible: yes

警告

Toxicity: Standard Handling (A)

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他說明

Melis, M. R. et al. 2005. Neurosci. Lett.379, 59.
Bernaerts, P. et al. 2003. Behav. Brain Res.142, 41.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable