推荐产品
product name
寡霉素, A mixture of A, B, and C isomers.
品質等級
化驗
≥90% (mixture of A, B, and C isomers, HPLC)
形狀
powder
製造商／商標名
Calbiochem®
儲存條件
OK to freeze
顏色
white
運輸包裝
ambient
儲存溫度
−20°C
InChI
1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13+,17-15-,21-18+
InChI 密鑰
MNULEGDCPYONBU-ZUSSGZTJSA-N
一般說明
A、B和C异构体的混合物。一种大环内酯类抗生素，可抑制膜结合线粒体ATP合成酶，从而阻止磷酸基转移。诱导人淋巴母细胞和其他哺乳动物细胞凋亡。
生化／生理作用
主要靶标
膜结合线粒体ATP酶（F1）
膜结合线粒体ATP酶（F1）
产品不与ATP竞争。
可逆：否
细胞渗透性：否
警告
毒性：刺激性（B）
重構
在重悬后分装并冻存于冰箱（-20°C。储备溶液在-20°C下可稳定保存2个月。
其他說明
Wolvetang, E.J., et al. 1994.FEBS Lett.339, 40.
Amoroso, S., et al. 1993.J. Pharmacol.Exp.Ther.264, 515.
Brustovetsky, N.N., et al. 1993.FEBS Lett.315, 233.
Nagamune, H., et al. 1993.Biochim.Biophys.Acta1141, 231.
Amoroso, S., et al. 1993.J. Pharmacol.Exp.Ther.264, 515.
Brustovetsky, N.N., et al. 1993.FEBS Lett.315, 233.
Nagamune, H., et al. 1993.Biochim.Biophys.Acta1141, 231.
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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