444896

MAS 7

A cell-permeable, amphiphilic, mastoparan analog with five-fold greater potency than Mastoparan.

• 别名: MAS 7
• 经验公式（希尔记法）: C₆₇H₁₂₄N₁₈O₁₅
• CAS号: 145854-59-7
• 分子量: 1421.81
• MDL號碼: MFCD00144726
• 分類程式碼代碼: 51111800
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze
• 顏色: white
• 溶解度: water: 5 mg/mL
• 運輸包裝: ambient
• 儲存溫度: −20°C
• InChI: 1S/C67H124N18O15/c1-18-38(12)53(71)67(100)85-51(32-52(70)86)66(99)84-50(31-37(10)11)64(97)79-45(24-20-22-26-69)61(94)75-42(16)58(91)82-47(28-34(4)5)62(95)76-39(13)55(88)73-40(14)57(90)81-48(29-35(6)7)63(96)77-41(15)56(89)78-44(23-19-21-25-68)60(93)74-43(17)59(92)83-49(30-36(8)9)65(98)80-46(54(72)87)27-33(2)3/h33-51,53H,18-32,68-69,71H2,1-17H3,(H2,70,86)(H2,72,87)(H,73,88)(H,74,93)(H,75,94)(H,76,95)(H,77,96)(H,78,89)(H,79,97)(H,80,98)(H,81,90)(H,82,91)(H,83,92)(H,84,99)(H,85,100)/t38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,53-/m0/s1
• InChI 密鑰: HOLQXBRPSSZJMZ-FGRXCANLSA-N

说明

一般說明

A cell-permeable, amphiphilic, mastoparan analog with five-fold greater potency than Mastoparan Cat. No. 444898. An activator of α-subunit of G-proteins. Evokes rapid upregulation of FAK tyrosine phosphorylation via activation of G-proteins.

Mastoparan analog with five-fold greater potency than mastoparan. An activator of the α-subunit of G -proteins. Evokes a rapid upregulation of FAK tyrosine phosphorylation via activation of G-proteins.

生化／生理作用

Cell permeable: yes

Primary Target
α-subunit of G-proteins

Product does not compete with ATP.

Reversible: no

包裝

Yes

警告

Toxicity: Standard Handling (A)

序列

H-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Ala-Leu-Leu-NH₂

外觀

Supplied as a trifluoroacetate salt.

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他說明

Mironov, S.L., and Richter, D.W. 2000. Brain Res.853, 60.
Park, H.S., et al. 2000. Biochim. Biophys. Acta1484, 151.
Zhang, C., et al. 1996. FEBS Lett. 386, 185.
Leyte, A., et al. 1992. EMBO J.11 4795.
Higashijima, T., et al. 1990. J. Biol. Chem.265, 14176.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable