208670

Calmodulin, His•Tag^® Human, Recombinant

Calmodulin, His•Tag Human, Recombinant, is a full-length, recombinant human calmodulin fused to a His•Tag sequence at the N-terminus. Contains four functional Ca²⁺-binding sites.

• 别名: Calmodulin, Human, Recombinant
• 分類程式碼代碼: 12352202
• NACRES: NA.77

属性

• 生物源: human
• 品質等級: 100
• 化驗: >90% (SDS-PAGE)
• 形狀: liquid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; avoid repeated freeze/thaw cycles
• 運輸包裝: wet ice
• 儲存溫度: −70°C

说明

一般說明

Full-length, recombinant human calmodulin fused to a His•Tag sequence at the N-terminus. Contains four functional Ca²⁺-binding sites (aa 20-31; aa 56-67; aa 93-104; aa 129-140) with EF-hands (aa 7-42; aa 43-78; aa 80-115; aa 116-148); and a ubiquitination site at Lys²¹. This preparation is qualified for use as a substrate for protein tyrosine kinases in in vitro assays. Through its interaction with Ca²⁺, calmodulin mediates the control of a large number of enzymes, including protein kinases and phosphatases. It is expected to be phosphorylated at Thr⁴⁴ by CaMK4. In addition, it serves as a substrate for various protein tyrosine kinases.

包裝

Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

外觀

In PBS, 0.2% Protease Inhibitor Cocktail Set VII (Cat. No. 539138).

重構

Following initial thaw, aliquot and freeze (-70°C).

其他說明

Chou, J.J., et al. 2001.Nat. Struct. Biol.8, 990.
Lennon, G., et al. 1996.Genomics33, 151.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable