219385

Cathepsin B Inhibitor II

The Cathepsin B Inhibitor II controls the biological activity of Cathepsin B. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

• 别名: Cathepsin B Inhibitor II, Ac-LVK-CHO
• 经验公式（希尔记法）: C₁₉H₃₆N₄O₄
• 分子量: 384.51
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥95% (HPLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze
• 顏色: white
• 溶解度: water: 1 mg/mL
• 運輸包裝: ambient
• 儲存溫度: −70°C

说明

一般說明

A more active lysinal analog of Leupeptin (Cat. No. 108975). A more potent inhibitor of cathepsin B (IC₅₀ = 4 nM) compared to leupeptin (IC₅₀ = 310 nM).

Lysinal analog of Leupeptin (Cat. No. 108975). A more potent inhibitor of cathepsin B (IC₅₀ = 4 nM) than of leupeptin (IC₅₀ = 310 nM). Note: this peptide forms cyclic isomers.

Note: this peptide forms cyclic isomers.

生化／生理作用

Cell permeable: no

Primary Target
cathepsin B

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 4 nM against cathepsin B

警告

Toxicity: Standard Handling (A)

序列

Ac-Leu-Val-lysinal

重構

Following reconstitution aliquot and freeze (-70°C). Stock solutions are stable for up to 1 month at -70°C.

其他說明

McConnell, R.M., et al. 1993. J. Med. Chem. 36, 1084.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable