推荐产品
product name
D-(–)-2-氨基-5-膦酰戊酸, Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used as a competitive NMDA receptor antagonist.
品質等級
化驗
≥97% (HPLC)
形狀
solid
製造商/商標名
Calbiochem®
儲存條件
OK to freeze
desiccated (hygroscopic)
protect from light
顏色
white
溶解度
dilute aqueous base: 1 mg/mL
water: 1 mg/mL
運輸包裝
ambient
儲存溫度
2-8°C
InChI
1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)/p-2/t4-/m1/s1
InChI 密鑰
VOROEQBFPPIACJ-SCSAIBSYSA-L
一般說明
一种DL-2-氨基-5-膦基戊酸(AP5)的活性对映体,是一种常用的竞争性NMDA受体拮抗剂。
一种DL-2-氨基-5-膦基戊酸(AP5)的活性对映体,通常用作竞争性NMDA受体拮抗剂。还抑制辣椒素诱导的脊髓物质P的释放。
生化/生理作用
主要靶标
NMDA受体拮抗剂
NMDA受体拮抗剂
产物不与ATP竞争。
可逆:否
细胞渗透性:否
警告
毒性:刺激性(B)
重構
复溶后,等分并冷冻保存(-20°C)。储备液在-20°C条件下可稳定保存6个月。
其他說明
Malcangio, M., et al. 1998.Br. J. Pharmacol.125, 1625.
Schulte, M.K., et al. 1994.Brain Res. 649, 203.
Davis, S., et al. 1992.J. Neurosci. 12, 21.
Schulte, M.K., et al. 1994.Brain Res. 649, 203.
Davis, S., et al. 1992.J. Neurosci. 12, 21.
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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