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Merck
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Key Documents

14-444-M

Sigma-Aldrich

PKC θ Protein, active, 10 µg

Active, recombinant full-length human PKC theta with a C-terminal 6His-tag. For use in Kinase Assays.

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About This Item

分類程式碼代碼:
12352202
eCl@ss:
32160405
NACRES:
NA.41

生物源

human

品質等級

100

重組細胞

expressed in Sf21 cells

分子量

Mw 83 kDa

製造商／商標名

Upstate®

技術

activity assay: suitable (kinase)

NCBI登錄號

NM_006257.2

UniProt登錄號

Q04759

基因資訊

human ... PRKCQ(5588)

一般說明

Product Source: expressed in Sf21 cells
Recombinant full-length human PKC theta with a C-terminal 6His-tag

PKC Lipid activator (Catalog # 20-133) is required for use.

生化／生理作用

Protein Target: PKCθ
Target Sub-Family: AGC

品質

routinely evaluated by phosphorylation of Histone H1 substrate in vitro

外觀

immobilized nickel affinity chromatography

儲存和穩定性

6 months at -70 °C

其他說明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H317

危險分類

Skin Sens. 1

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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G Baier et al.
The Journal of biological chemistry, 268(7), 4997-5004 (1993-03-05)
Members of the protein kinase C (PKC) family of serine/threonine kinases play a key role in regulating the differentiation and growth of diverse cell types and, to date, the cloning of seven mammalian PKC genes encoding eight distinct isoforms has
B Bauer et al.
The Journal of biological chemistry, 276(34), 31627-31634 (2001-06-19)
Protein kinase C theta (PKC theta) is known to induce NF-kappa B, an essential transcriptional element in T cell receptor/CD28-mediated interleukin-2 production but also T cell survival. Here we provide evidence that PKC theta is physically and functionally coupled to

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