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Merck

1.42020

SAFC

环糊精HPB

EMPROVE® EXPERT, Ph. Eur., NF

制药生产

别名:

Cyclodextrin HPB, (2-Hydroxypropyl)-β-Cyclodextrin, HP-B-CD, Hydroxypropyl Betadex

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About This Item

线性分子式:
C42H70-nO35 · (C3H7O)n
分類程式碼代碼:
12352201

agency

NF
Ph. Eur.

品質等級

產品線

EMPROVE® EXPERT

形狀

solid

分子量

avg mol wt 1387.2 g/mol

pH值

5.0-7.0 (20 g/L in H2O)

溶解度

450 g/L

應用

liquid formulation
ophthalmics
pharmaceutical
solid formulation
solubility enhancement

儲存溫度

15-25°C

一般說明

When working on a pharmaceutical formulation, there are specific considerations to make and challenging hurdles to take before you can successfully launch your final drug product - formulation stability, release kinetics and bioavailability limitations just to name a few. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

應用

Cyclodextrin HPB (hydroxypylated β-cyclodextrin) can be used to strongly increase solubility of active pharmaceutical ingredients (APIs) by forming API:cyclodextrin inclusion complexes. It can also increase API stability and safety as well as mask undesired odors and tastes. The broad application range of Cyclodextrin HPB comprises liquid, semi-solid and solid formulations, as well as diverse routes of administration. Due to its low microbial and endotoxin limits, Cyclodextrin HPB Emprove® Expert is especially suitable for high-risk applications.

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

752.0 °F

閃點(°C)

> 400 °C


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