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Merck
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Key Documents

12667-M

Sigma-Aldrich

Albumin, Human Serum, 30% Aqueous Solution

别名:

Albumin, Human Serum, 30% Aqueous Solution

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About This Item

CAS号:
MDL號碼:
分類程式碼代碼:
12352202

化驗

≥95% (agarose gel electrophoresis)

形狀

liquid

製造商/商標名

Calbiochem®

儲存條件

OK to freeze

儲存溫度

2-8°C

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

InChI 密鑰

QYSGYZVSCZSLHT-UHFFFAOYSA-N

一般說明

Human serum albumin (HSA) is a soluble, globular, and unglycosylated monomeric protein, which is abundantly found in the plasma. It contains three homologous domains, numbered I, II, and III. Each domain is divided into subdomains A and B comprising common structural motifs. The HSA gene is localized to the human chromosome 4q13.3.

生化/生理作用

Human serum albumin (HSA) acts as the most important carrier protein for fatty acids, thyroid hormones, and steroids. It serves as a supplement in cell culture medium for the generation of vaccines and pharmaceuticals. HSA acts as a valuable biomarker for diseases, such as severe acute graft-versus-host disease, cancer, and rheumatoid arthritis. It is clinically used to treat serious burn injuries, hemorrhagic shock, hypoproteinemia, and fetal erythroblastosis. HSA is used in biological applications including nano delivery of drugs, carrier of oxygen, and fusion of peptides.

警告

Toxicity: Standard Handling (A)

外觀

30% solution in 20 mM Tris-HCl, 0.1% NaN₃, pH 6-8.

準備報告

Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

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Yang He et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(47), 19078-19083 (2011-11-02)
Human serum albumin (HSA) is widely used in clinical and cell culture applications. Conventional production of HSA from human blood is limited by the availability of blood donation and the high risk of viral transmission from donors. Here, we report
Gabriella Fanali et al.
Molecular aspects of medicine, 33(3), 209-290 (2012-01-11)
Human serum albumin (HSA), the most abundant protein in plasma, is a monomeric multi-domain macromolecule, representing the main determinant of plasma oncotic pressure and the main modulator of fluid distribution between body compartments. HSA displays an extraordinary ligand binding capacity

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