1.00164

硼酸

cryst., EMPROVE^® API, Ph. Eur., BP, NF

• 别名: Orthoboric acid, Trihydroxidoboron
• 线性分子式: H₃BO₃
• CAS号: 10043-35-3
• 分子量: 61.83
• MDL號碼: MFCD00011337
• 分類程式碼代碼: 12352106
• 酶委員會索引編號: 233-139-2

属性

• agency: BP; NF; Ph. Eur.
• 品質等級: 600
• 蒸汽壓力: 2.6 mmHg ( 20 °C)
• 產品線: EMPROVE^® API
• 化驗: 99.5-100.5% (alkalimetric)
• 形狀: solid
• 效力: 2660 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rat)
• pH值: 3.8-4.8 (20 °C, 33 g/L in H₂O)
• mp: 160 °C (dec.) (lit.)
• 溶解度: 49.2 g/L
• 密度: 1.489 g/cm³ at 23 °C
• 體積密度: 400‑600 kg/m³
• 負離子痕跡: sulfate (SO₄^2-): ≤0.04%
• 正離子痕跡: As: ≤0.0001%; heavy metals (as Pb): ≤0.0015%
• 應用: liquid formulation; ophthalmics; parenterals; pharmaceutical; semi-solid formulation
• 儲存溫度: 2-25°C
• SMILES 字串: OB(O)O
• InChI: 1S/BH3O3/c2-1(3)4/h2-4H
• InChI 密鑰: KGBXLFKZBHKPEV-UHFFFAOYSA-N

说明

一般說明

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

應用

Boric acid as an active ingredient is used in ophthalmic drugs, as antiseptic for cuts and burns, as well as antibacterial for dermatological treatments such as acne and athlete foot. Boric acid Emprove^® API is manufactured according to ICH Q7 guidelines. A CEP and an US-DMF are available.

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形圖: GHS08
• 訊號詞: Danger
• 危險聲明: H360FD
• 防範說明: P201 - P202 - P280 - P308 + P313 - P405 - P501
• 危險分類: Repr. 1B
• 儲存類別代碼: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable