推荐产品
生物源
rabbit
品質等級
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
純化經由
affinity chromatography
物種活性
human
製造商／商標名
Upstate®
技術
western blot: suitable
同型
IgG
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
phosphorylation (pTyr342)
基因資訊
human ... PTK6(5753)
特異性
可识别酪氨酸342的人磷酸化-Brk。
免疫原
KLH缀合的合成肽对应于包含人Brk的Tyr342的氨基酸。
應用
抗磷酸化-Brk（Tyr342）抗体是针对磷酸化-Brk（Tyr342）的抗体，可用于WB。
研究子类别
肿瘤标记物
肿瘤标记物
研究类别
细胞凋亡 & 癌症
细胞凋亡 & 癌症
品質
已通过免疫印迹进行常规评估。
標靶描述
~50 kDa
外觀
免疫亲和纯化
纯化的兔多克隆抗体，溶于含有0.1 M Tris-甘氨酸（pH 7.4）、150 mM NaCl和0.05％叠氮化钠的缓冲液中。
儲存和穩定性
自收到之日起，在2-8°C条件下可稳定保存1年。
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
L Liu et al.
Oncogene, 25(35), 4904-4912 (2006-03-29)
Breast tumor kinase (Brk) is a non-receptor tyrosine kinase distantly related to the Src family kinase. It is expressed in more than 60% of breast tumors, but the biological role of this kinase remains to be determined. Only a limited
Priya S Mathur et al.
Molecular cancer research : MCR, 14(6), 563-573 (2016-03-18)
Disruption of the gene encoding Protein Tyrosine Kinase 6 (Ptk6) delayed differentiation and increased growth in the mouse intestine. However, Ptk6-null mice were also resistant to azoxymethane-induced colon tumorigenesis. To further explore functions of PTK6 in colon cancer, expression of
Haoqun Qiu et al.
Oncogene, 24(36), 5656-5664 (2005-05-05)
Breast tumor kinase (Brk) is a member of the Frk family of nonreceptor tyrosine kinases that is overexpressed in a high percentage of human breast tumors. The downstream substrates and effectors of Brk remain largely unidentified. In this study, we
Wanian M Alwanian et al.
The Journal of biological chemistry, 298(11), 102584-102584 (2022-10-14)
Expression of Protein tyrosine kinase 6 (PTK6) is upregulated in several human solid tumors, and it has oncogenic roles in prostate and breast cancer. PTK6 and SRC kinase are distantly related, share many substrates, and often regulate the same signaling
Maoyu Peng et al.
Oncotarget, 5(15), 6038-6048 (2014-08-26)
Protein Tyrosine kinase 6 (PTK6/BRK) is overexpressed in the majority of human breast tumors and breast tumor cell lines. It is also expressed in normal epithelial linings of the gastrointestinal tract, skin, and prostate. To date, expression of PTK6 has
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