推荐产品
生物源
mouse
品質等級
抗體表格
ascites fluid
抗體產品種類
primary antibodies
無性繁殖
PRK8, monoclonal
物種活性
human, mouse
製造商／商標名
Upstate®
技術
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
目標翻譯後修改
unmodified
基因資訊
human ... PARK2(5071)
特異性
Parkin
免疫原
Full length recombinant human Parkin. Epitope has been mapped to the second ring domain (aa 399-465)
應用
Anti-Parkin Antibody, clone PRK8 detects level of Parkin & has been published & validated for use in IP, WB, IC, IH.
品質
routinely evaluated by immunoblot on RIPA lysates from HEK293 cells
標靶描述
52kDa May be observed as a doublet at 52 and 46kDa
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
Are ubiquitination pathways central to Parkinson's disease?
Giasson, Benoit I and Lee, Virginia M-Y
Cell, 114, 1-8 (2003)
Molecular pathways of neurodegeneration in Parkinson's disease.
Dawson, Ted M and Dawson, Valina L
Science (New York, N.Y.), 302, 819-822 (2003)
Genotype-phenotype correlation: familial Parkinson disease.
Mori, Hideo, et al.
Neuropathology : Official Journal of the Japanese Society of Neuropathology, 23, 90-94 (2003)
Nobutaka Hattori et al.
Lancet (London, England), 364(9435), 722-724 (2004-08-25)
The cause and pathogenesis of Parkinson's disease remain unknown; mitochondrial dysfunction, oxidative damage, environmental factors, and genetic predisposition might all be involved. Identification of the causative genes for familial Parkinson's diseases allow study of the pathogenesis of the disease at
Keiji Tanaka et al.
Biochimica et biophysica acta, 1695(1-3), 235-247 (2004-12-02)
The ubiquitin-proteasome system (UPS) is important for intracellular proteolysis, and is responsible for a diverse array of biologically important cellular processes, such as cell-cycle progression, signaling cascades and developmental programs. This system is also involved in the protein quality control
商品
Autophagy is a highly regulated process that is involved in cell growth, development, and death. In autophagy cells destroy their own cytoplasmic components in a very systematic manner and recycle them.
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