推荐产品
生物源
mouse
品質等級
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
99D, monoclonal
物種活性
rat, human, mouse
製造商／商標名
Upstate®
技術
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同型
IgG1κ
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
目標翻譯後修改
unmodified
基因資訊
human ... BIN1(274)
mouse ... Bin1(30948)
特異性
Bin1
免疫原
Partial fusion protein corresponding to amino acids 189-398 of human Bin1. Clone 99D
應用
Anti-Bin1 Antibody, clone 99D is an antibody against Bin1 for use in IP, WB, IH.
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
BCL2 & Inhibition
BCL2 & Inhibition
品質
routinely evaluated by immunoblot on RIPA lysate of C2C12 cells.
標靶描述
56kDa
聯結
Replaces: MAB4131
外觀
Protein G Chromatography
0.1M Tris-glycine, pH 7.4, containing 0.05% sodium azide
Format: Purified
儲存和穩定性
1 year at -20°C
其他說明
Due to license agreement restrictions, this product cannot be purchased for resale.
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Suppression of MEK/ERK signalling by Myc: role of Bin-1.
Telfer, JF; Urquhart, J; Crouch, DH
Cellular Signalling null
R Wechsler-Reya et al.
Cancer research, 57(15), 3258-3263 (1997-08-01)
BIN1 is a putative tumor suppressor that was identified in a genetic screen for polypeptides that interact with the MYC oncoprotein. Using a set of six monoclonal antibodies, we identified and examined biochemical features and localization of cellular BIN1. Epitope
Tiago Mendes et al.
Current protocols in cell biology, 86(1), e100-e100 (2019-12-27)
The proximity ligation assay (PLA) allows the detection and subcellular localization of protein-protein interactions with high specificity. We recently developed a high-content screening model based on primary hippocampal neurons cultured in 384-well plates and screened a library of ∼1100 compounds
R J Wechsler-Reya et al.
Molecular and cellular biology, 18(1), 566-575 (1998-01-07)
Bin1 is a Myc-interacting protein with features of a tumor suppressor. The high level of Bin1 expression in skeletal muscle prompted us to investigate its role in muscle differentiation. Significant levels of Bin1 were observed in undifferentiated C2C12 myoblasts, a
Maxime Sartori et al.
Acta neuropathologica, 138(4), 631-652 (2019-05-09)
The bridging integrator 1 gene (BIN1) is a major genetic risk factor for Alzheimer's disease (AD). In this report, we investigated how BIN1-dependent pathophysiological processes might be associated with Tau. We first generated a cohort of control and transgenic mice
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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