推荐产品
生物源
mouse
品質等級
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
99D, monoclonal
物種活性
rat, human, mouse
製造商/商標名
Upstate®
技術
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同型
IgG1κ
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
目標翻譯後修改
unmodified
基因資訊
human ... BIN1(274)
mouse ... Bin1(30948)
特異性
Bin1
免疫原
对应于人 Bin1氨基酸 189-398的部分融合蛋白 克隆99D
應用
抗-Bin1抗体(克隆99D)是用于IP、WB、 IH.的抗-Bin1 抗体。
研究子类别
BCL2 & 抑制
BCL2 & 抑制
研究类别
细胞凋亡 & 癌症
细胞凋亡 & 癌症
品質
通过免疫印迹对C2C12细胞的RIPA裂解液进行了常规评估
標靶描述
56kDa
聯結
替代:MAB4131
外觀
0.1M Tris-甘氨酸,pH 7.4,含0.05%叠氮化钠
形式:纯化
蛋白G色谱
儲存和穩定性
在-20°C下保存1年
其他說明
由于许可协议限制,无法购买该产品进行转售。
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Suppression of MEK/ERK signalling by Myc: role of Bin-1.
Cellular Signalling null
Cancer research, 57(15), 3258-3263 (1997-08-01)
BIN1 is a putative tumor suppressor that was identified in a genetic screen for polypeptides that interact with the MYC oncoprotein. Using a set of six monoclonal antibodies, we identified and examined biochemical features and localization of cellular BIN1. Epitope
Current protocols in cell biology, 86(1), e100-e100 (2019-12-27)
The proximity ligation assay (PLA) allows the detection and subcellular localization of protein-protein interactions with high specificity. We recently developed a high-content screening model based on primary hippocampal neurons cultured in 384-well plates and screened a library of ∼1100 compounds
Molecular and cellular biology, 18(1), 566-575 (1998-01-07)
Bin1 is a Myc-interacting protein with features of a tumor suppressor. The high level of Bin1 expression in skeletal muscle prompted us to investigate its role in muscle differentiation. Significant levels of Bin1 were observed in undifferentiated C2C12 myoblasts, a
Acta neuropathologica, 138(4), 631-652 (2019-05-09)
The bridging integrator 1 gene (BIN1) is a major genetic risk factor for Alzheimer's disease (AD). In this report, we investigated how BIN1-dependent pathophysiological processes might be associated with Tau. We first generated a cohort of control and transgenic mice
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