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Merck

LM1901

Avanti

17:0-20:4pi (4) P

Avanti Research - A Croda Brand LM1901, powder

别名:

1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-myo-inositol-4′-phosphate) (ammonium salt)

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About This Item

经验公式(希尔记法):
C46H88N2O16P2
分子量:
987.14
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

powder

製造商/商標名

Avanti Research - A Croda Brand LM1901

包裝

1 ea of 1 × (with stopper and crimp cap (LM1901-1EA))

應用

lipidomics
metabolomics

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](OP([O-])(O)=O)[C@@H](O)[C@H]1O)=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+]

InChI

1S/C46H82O16P2.2H3N/c1-3-5-7-9-11-13-15-17-19-20-21-23-25-27-29-31-33-35-40(48)60-38(36-58-39(47)34-32-30-28-26-24-22-18-16-14-12-10-8-6-4-2)37-59-64(56,57)62-46-43(51)41(49)45(42(50)44(46)52)61-63(53,54)55;;/h11,13,17,19,21,23,27,29,38,41-46,49-52H,3-10,

InChI 密鑰

PAUDLJVALNTADC-YGZOHRIRSA-N

應用

1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-myo-inositol-4′;-phosphate) (ammonium salt) has been used:
  • as a lipid standard in ultra-performance liquid chromatography-tandem mass spectrometry (UPLC/MS)
  • to spike into extracts of phosphoinositides (PIPs) brain sample for mass spectrometric characterization and quantification of PIPs
  • as an internal standard for lipid extraction from Drosophila retinae

生化/生理作用

Phosphatidylinositol 4-phosphate (PI4P) acts as substrate for phosphatidylinositol-4-phosphate 5-kinase (PIP5K) enzymes. This accounts for the formation of phosphatidylinositol 4,5- bisphosphate (PI(4,5)P2), a membrane lipid, which aids in phospholipase C (PLC) signaling.

包裝

2 mL Amber Serum Vial with Stopper and Crimp Cap (LM1901-1EA)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

也與該產品經常一起購買

儲存類別代碼

11 - Combustible Solids


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Avishek Ghosh et al.
Bioscience reports, 39(10) (2019-10-28)
Phosphatidylinositol-5-phosphate (PI5P) is a low abundance lipid proposed to have functions in cell migration, DNA damage responses, receptor trafficking and insulin signalling in metazoans. However, studies of PI5P function are limited by the lack of scalable techniques to quantify its

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