跳转至内容
Merck
所有图片(1)

主要文件

查看所有文档

LM1302

Avanti

17:0-20:4 PS

Avanti Research™ - A Croda Brand LM1302, methanol solution

别名:

1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine (ammonium salt)

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C43H79N2O10P
CAS号:
1246304-53-9
分子量:
815.07
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

methanol solution

包裝

pkg of 1 × 1 mL (LM1302-1EA)

製造商／商標名

Avanti Research™ - A Croda Brand LM1302

濃度

~10 μg/mL (Refer to C of A for lot specific concentration.)

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[NH4+]

InChI 密鑰

PVYYHCZONIFDMV-SPTHKXBTSA-N

相关类别

一般說明

In humans, phosphoserine (PS) is present in the intracellular membranes and grey matter. It is localized to the nuclear envelope, endoplasmic reticulum, Golgi apparatus, outer mitochondrial membranes, plasma membranes and myelin.

應用

17:0-20:4 PS or 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine has been used as an internal standard:
  • in lipid extraction from isolated pure mitochondria for mass spectrometry (MS) analysis
  • for lipid quantification/analysis using liquid chromatography (LC)-MS
  • for phospholipid quantification by MS
  • in lysophospholipid acyltransferases (LPLAT) assay
  • in the preparation of total lipid extracts from lysosome samples by tert-butyl methyl ether (MTBE) lipid extraction protocol for analysis by LC-MS
  • for ratiometric quantification of phosphatidylserine (PS) using LC-MS

生化／生理作用

Phosphoserine (PS) maintains the nerve cell membrane and myelin sheath. It is found to be associated with cognitive disability in Alzheimer′s disease.

包裝

2 mL Amber Glass Sealed Ampule (LM1302-1EA)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes

儲存類別代碼

3 - Flammable liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

49.5 °F - closed cup

閃點（°C）

9.7 °C - closed cup

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 文件 section.

如需帮助，请联系 客户支持

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Di Ding et al.
Molecular neurobiology, 56(4), 2618-2639 (2018-07-28)
Neurons from the adult central nervous system (CNS) demonstrate limited mRNA transport and localized protein synthesis versus developing neurons, correlating with lower regenerative capacity. We found that deimination (posttranslational conversion of protein-bound arginine into citrulline) undergoes upregulation during early neuronal
Penelope Dimas et al.
eLife, 8 (2019-05-08)
Oligodendrocytes (OLs) support neurons and signal transmission in the central nervous system (CNS) by enwrapping axons with myelin, a lipid-rich membrane structure. We addressed the significance of fatty acid (FA) synthesis in OLs by depleting FA synthase (FASN) from OL
Ulrike Bruning et al.
Cell metabolism, 28(6), 866-880 (2018-08-28)
The role of fatty acid synthesis in endothelial cells (ECs) remains incompletely characterized. We report that fatty acid synthase knockdown (FASNKD) in ECs impedes vessel sprouting by reducing proliferation. Endothelial loss of FASN impaired angiogenesis in vivo, while FASN blockade reduced
Milena Vukotic et al.
Molecular cell, 67(3), 471-483 (2017-07-18)
Mutations in mitochondrial acylglycerol kinase (AGK) cause Sengers syndrome, which is characterized by cataracts, hypertrophic cardiomyopathy, and skeletal myopathy. AGK generates phosphatidic acid and lysophosphatidic acid, bioactive phospholipids involved in lipid signaling and the regulation of tumor progression. However, the

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门