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形狀
hexane solution
包裝
pkg of 1 × 1 mL (870608H-5mg)
製造商／商標名
Avanti Research™ - A Croda Brand 870608H
濃度
6.8 mg/mL (870608H-5mg)
脂質類型
phosphoglycerides
bioactive lipids
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
CCCCC[C@@H](O)/C=C/C(OC)OC
一般說明
4-羟基壬烯醛（4-HNE或HNE）是细胞内脂质过氧化产生的α,β-不饱和羟基烯醛。一些研究人员假设，4-HNE在从细胞周期事件到细胞粘附的多种途径中的细胞信号转导中发挥关键作用。
二甲基缩醛衍生物是更稳定的4-HNE形式，有利于化合物在使用过程中的长期保存。在酸存在下，很容易转化为4-HNE。
二甲基缩醛衍生物是更稳定的4-HNE形式，有利于化合物在使用过程中的长期保存。在酸存在下，很容易转化为4-HNE。
包裝
2mL棕色玻璃密封安瓿（870608H-5mg）
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
訊號詞
Danger
危險分類
Aquatic Chronic 2 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Inhalation - STOT SE 3
標靶器官
Central nervous system, Nervous system
儲存類別代碼
3 - Flammable liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
-14.8 °F - closed cup
閃點（°C）
-26.0 °C - closed cup
其他客户在看
Kamelija Zarkovic
Molecular aspects of medicine, 24(4-5), 293-303 (2003-08-02)
The development of oxidative stress, in which production of highly reactive oxygen species (ROS) overwhelms antioxidant defenses, is a feature of many neurological diseases: ischemic, inflammatory, metabolic and degenerative. Oxidative stress is increasingly implicated in a number of neurodegenerative disorders
Rajendra Sharma et al.
European journal of biochemistry, 271(9), 1690-1701 (2004-04-21)
4-Hydroxy-2-trans-nonenal (4-HNE), one of the major end products of lipid peroxidation, has been shown to induce apoptosis in a variety of cell lines. It appears to modulate signaling processes in more than one way because it has been suggested to
Yogesh C Awasthi et al.
Free radical biology & medicine, 37(5), 607-619 (2004-08-04)
4-Hydroxynonenal (HNE), one of the major end products of lipid peroxidation, has been shown to be involved in signal transduction and available evidence suggests that it can affect cell cycle events in a concentration-dependent manner. Glutathione S-transferases (GSTs) can modulate
Neven Zarkovic
Molecular aspects of medicine, 24(4-5), 281-291 (2003-08-02)
The review is focused on the currently major aspect of 4-hydroxynonenal (HNE) research--studies that combine biological activities of the aldehyde together with the methods of its identification in cells and tissues. Because there were some excellent reviews on HNE published
N Zarković et al.
Life sciences, 65(18-19), 1901-1904 (1999-11-27)
Immunohistochemical analysis of the distribution of the lipid peroxidation product 4-hydroxynonenal (HNE) in the brain of baboons exposed to experimental hemorrhagic traumatic shock or sepsis showed that systemic oxidative stress and the thereby generated HNE affect the blood:brain barrier and
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