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860636P

Avanti

葡糖基(β) 鞘氨醇-d5

Avanti Research™ - A Croda Brand

别名:

D-葡萄糖基-β-1,1′-D-赤-鞘氨醇-d5

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About This Item

经验公式（希尔记法）:
C24H42D5NO7
CAS号:
1347831-14-4
分子量:
466.66
MDL號碼:
MFCD35071465
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

powder

包裝

pkg of 1 × 1 mg (860636P-1mg)

製造商／商標名

Avanti Research™ - A Croda Brand

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@](/C=C/CCCCCCCCCCCC([2H])(C([2H])([2H])[2H])[2H])(O)[C@](N)([H])CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O

InChI

1S/C24H47NO7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(27)18(25)17-31-24-23(30)22(29)21(28)20(16-26)32-24/h14-15,18-24,26-30H,2-13,16-17,25H2,1H3/b15-14+/t18-,19+,20+,21+,22-,23+,24+/m0/s1/i1D3,2D2

InChI 密鑰

HHJTWTPUPVQKNA-JCMYXXMQSA-N

相关类别

應用

葡萄糖基（β）鞘氨醇-d5已用作内标，用于通过液相色谱-串联质谱法定量各种样品中的溶血己糖基神经酰胺。

生化／生理作用

葡萄糖基鞘氨醇具有调节脑微粒体中Ca2+释放的能力。它作为戈谢病（GD）的潜在生物标记物。

包裝

5 mL棕色玻璃螺旋盖小瓶（860636P-1mg）

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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产品编号
说明
价格

儲存類別代碼

11 - Combustible Solids

历史批次信息供参考:

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Glucosylsphingosine is a highly sensitive and specific biomarker for primary diagnostic and follow-up monitoring in Gaucher disease in a non-Jewish, Caucasian cohort of Gaucher disease patients
Rolfs A, et al.
PLoS ONE, 8(11) (2013)
LC-MS/MS multiplex analysis of lysosphingolipids in plasma and amniotic fluid: a novel tool for the screening of sphingolipidoses and Niemann-Pick type C disease
Pettazzoni M, et al.
PLoS ONE, 12(7) (2017)
LC-MS/MS multiplex analysis of lysosphingolipids in plasma and amniotic fluid: a novel tool for the screening of sphingolipidoses and Niemann-Pick type C disease
Pettazzoni M, et al.
Testing, 12(7) (2017)
Mercedes Roca-Espiau et al.
Journal of orthopaedic surgery and research, 14(1), 383-383 (2019-11-23)
Chronic fatigue (CFg) is a prevalent symptom in Gaucher disease (GD) at diagnosis (79%) and remains in a quarter of patients after years of therapy. Bone abnormalities are present in over 70% and peripheral neuropathy in about 11% of the
Magali Pettazzoni et al.
PloS one, 12(7), e0181700-e0181700 (2017-07-28)
The biological diagnosis of sphingolipidoses currently relies on the measurement of specific enzymatic activities and/or genetic studies. Lysosphingolipids have recently emerged as potential biomarkers of sphingolipidoses and Niemann-Pick type C in plasma. We developed a sensitive and specific method enabling
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