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形狀
powder
包裝
pkg of 1 × 10 mg (860512P-10mg)
pkg of 1 × 25 mg (860512P-25mg)
pkg of 1 × 5 mg (860512P-5mg)
製造商／商標名
Avanti Research™ - A Croda Brand
脂質類型
sphingolipids
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
OC[C@]([H])(NC(CCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI
1S/C30H59NO3/c1-3-5-7-9-11-13-14-15-16-18-19-21-23-25-29(33)28(27-32)31-30(34)26-24-22-20-17-12-10-8-6-4-2/h23,25,28-29,32-33H,3-22,24,26-27H2,1-2H3,(H,31,34)/b25-23+/t28-,29+/m0/s1
InChI 密鑰
HXFPPRPLRSPNIB-VARSQMIESA-N
一般說明
C12神经酰胺（d18：1/12：0）是一种含有鞘氨醇和十二烷酸的合成神经酰胺。
應用
C12神经酰胺（d18:1/12:0）或N-月桂酰-D-赤型-鞘氨醇已用于：
- 作为脂质标准品，用于优化液相色谱-质谱（LC-MS）法条件
- 作为U87MG（人胶质瘤细胞系）中脂质提取的内标
- 作为液相色谱-质谱（LC-MS）法测定大鼠组织中神经酰胺含量的内标
生化／生理作用
神经酰胺是鞘脂的信号传导，与调节应激反应和炎症有关。它还调节细胞生长停滞、分化和凋亡。
包裝
5 mL棕色玻璃螺旋盖小瓶（860512P-10mg）
5 mL棕色玻璃螺旋盖小瓶（860512P-25mg）
5 mL棕色玻璃螺旋盖小瓶（860512P-5mg）
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
也與該產品經常一起購買
产品编号
说明
价格
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
Gergely Karsai et al.
The Journal of biological chemistry, 295(7), 1889-1897 (2019-12-22)
Sphingolipids (SLs) are structurally diverse lipids that are defined by the presence of a long-chain base (LCB) backbone. Typically, LCBs contain a single Δ4E double bond (DB) (mostly d18:1), whereas the dienic LCB sphingadienine (d18:2) contains a second DB at
Mónica Narváez-Rivas et al.
Journal of chromatography. A, 1440, 123-134 (2016-03-02)
The goal of untargeted lipidomics is to have high throughput, yet comprehensive and unambiguous identification and quantification of lipids. Novel stationary phases in LC separation and new mass spectrometric instruments capable of high mass resolving power and faster scanning rate
Sonia Hernández-Tiedra et al.
Autophagy, 12(11), 2213-2229 (2016-11-02)
Autophagy is considered primarily a cell survival process, although it can also lead to cell death. However, the factors that dictate the shift between these 2 opposite outcomes remain largely unknown. In this work, we used Δ9-tetrahydrocannabinol (THC, the main
Megan Melland-Smith et al.
Autophagy, 11(4), 653-669 (2015-04-09)
Bioactive sphingolipids including ceramides are involved in a variety of pathophysiological processes by regulating cell death and survival. The objective of the current study was to examine ceramide metabolism in preeclampsia, a serious disorder of pregnancy characterized by oxidative stress
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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